Image and Video Processing (eess.IV)

Abstract: Breast cancer early detection is crucial for improving patient outcomes. The Institut Catal\`a de la Salut (ICS) has launched the DigiPatICS project to develop and implement artificial intelligence algorithms to assist with the diagnosis of cancer. In this paper, we propose a new approach for facing the color normalization problem in HER2-stained histopathological images of breast cancer tissue, posed as an style transfer problem. We combine the Color Deconvolution technique with the Pix2Pix GAN network to present a novel approach to correct the color variations between different HER2 stain brands. Our approach focuses on maintaining the HER2 score of the cells in the transformed images, which is crucial for the HER2 analysis. Results demonstrate that our final model outperforms the state-of-the-art image style transfer methods in maintaining the cell classes in the transformed images and is as effective as them in generating realistic images.

Abstract: Medical imaging is an essential tool for diagnosing various healthcare diseases and conditions. However, analyzing medical images is a complex and time-consuming task that requires expertise and experience. This article aims to design a decision support system to assist healthcare providers and patients in making decisions about diagnosing, treating, and managing health conditions. The proposed architecture contains three stages: 1) data collection and labeling, 2) model training, and 3) diagnosis report generation. The key idea is to train a deep learning model on a medical image dataset to extract four types of information: the type of image scan, the body part, the test image, and the results. This information is then fed into ChatGPT to generate automatic diagnostics. The proposed system has the potential to enhance decision-making, reduce costs, and improve the capabilities of healthcare providers. The efficacy of the proposed system is analyzed by conducting extensive experiments on a large medical image dataset. The experimental outcomes exhibited promising performance for automatic diagnosis through medical images.

Abstract: Diffusion models were initially developed for text-to-image generation and are now being utilized to generate high quality synthetic images. Preceded by GANs, diffusion models have shown impressive results using various evaluation metrics. However, commonly used metrics such as FID and IS are not suitable for determining whether diffusion models are simply reproducing the training images. Here we train StyleGAN and diffusion models, using BRATS20 and BRATS21 datasets, to synthesize brain tumor images, and measure the correlation between the synthetic images and all training images. Our results show that diffusion models are much more likely to memorize the training images, especially for small datasets. Researchers should be careful when using diffusion models for medical imaging, if the final goal is to share the synthetic images.