Image and Video Processing (eess.IV)

Abstract: Automated medical image segmentation can assist doctors to diagnose faster and more accurate. Deep learning based models for medical image segmentation have made great progress in recent years. However, the existing models fail to effectively leverage Transformer and MLP for improving U-shaped architecture efficiently. In addition, the multi-scale features of the MLP have not been fully extracted in the bottleneck of U-shaped architecture. In this paper, we propose an efficient U-shaped architecture based on Swin Transformer and multi-scale MLP, namely STM-UNet. Specifically, the Swin Transformer block is added to skip connection of STM-UNet in form of residual connection, which can enhance the modeling ability of global features and long-range dependency. Meanwhile, a novel PCAS-MLP with parallel convolution module is designed and placed into the bottleneck of our architecture to contribute to the improvement of segmentation performance. The experimental results on ISIC 2016 and ISIC 2018 demonstrate the effectiveness of our proposed method. Our method also outperforms several state-of-the-art methods in terms of IoU and Dice. Our method has achieved a better trade-off between high segmentation accuracy and low model complexity.

Abstract: Deep neural networks (DNNs) have promoted the development of computer aided diagnosis (CAD) systems for fundus diseases, helping ophthalmologists reduce missed diagnosis and misdiagnosis rate. However, the majority of CAD systems are data-driven but lack of medical prior knowledge which can be performance-friendly. In this regard, we innovatively proposed a human-in-the-loop (HITL) CAD system by leveraging ophthalmologists' eye-tracking information, which is more efficient and accurate. Concretely, the HITL CAD system was implemented on the multiple instance learning (MIL), where eye-tracking gaze maps were beneficial to cherry-pick diagnosis-related instances. Furthermore, the dual-cross-attention MIL (DCAMIL) network was utilized to curb the adverse effects of noisy instances. Meanwhile, both sequence augmentation module and domain adversarial module were introduced to enrich and standardize instances in the training bag, respectively, thereby enhancing the robustness of our method. We conduct comparative experiments on our newly constructed datasets (namely, AMD-Gaze and DR-Gaze), respectively for the AMD and early DR detection. Rigorous experiments demonstrate the feasibility of our HITL CAD system and the superiority of the proposed DCAMIL, fully exploring the ophthalmologists' eye-tracking information. These investigations indicate that physicians' gaze maps, as medical prior knowledge, is potential to contribute to the CAD systems of clinical diseases.

Abstract: In this paper, we provide an in-depth assessment on the Bj{\o}ntegaard Delta. We construct a large data set of video compression performance comparisons using a diverse set of metrics including PSNR, VMAF, bitrate, and processing energies. These metrics are evaluated for visual data types such as classic perspective video, 360{\deg} video, point clouds, and screen content. As compression technology, we consider multiple hybrid video codecs as well as state-of-the-art neural network based compression methods. Using additional performance points inbetween standard points defined by parameters such as the quantization parameter, we assess the interpolation error of the Bj{\o}ntegaard-Delta (BD) calculus and its impact on the final BD value. Performing an in-depth analysis, we find that the BD calculus is most accurate in the standard application of rate-distortion comparisons with mean errors below 0.5 percentage points. For other applications, the errors are higher (up to 10 percentage points), but can be reduced by a higher number of performance points. We finally come up with recommendations on how to use the BD calculus such that the validity of the resulting BD-values is maximized. Main recommendations include the use of Akima interpolation, the interpretation of relative difference curves, and the use of the logarithmic domain for saturating metrics such as SSIM and VMAF.

Abstract: Timely and affordable computer-aided diagnosis of retinal diseases is pivotal in precluding blindness. Accurate retinal vessel segmentation plays an important role in disease progression and diagnosis of such vision-threatening diseases. To this end, we propose a Multi-resolution Contextual Network (MRC-Net) that addresses these issues by extracting multi-scale features to learn contextual dependencies between semantically different features and using bi-directional recurrent learning to model former-latter and latter-former dependencies. Another key idea is training in adversarial settings for foreground segmentation improvement through optimization of the region-based scores. This novel strategy boosts the performance of the segmentation network in terms of the Dice score (and correspondingly Jaccard index) while keeping the number of trainable parameters comparatively low. We have evaluated our method on three benchmark datasets, including DRIVE, STARE, and CHASE, demonstrating its superior performance as compared with competitive approaches elsewhere in the literature.

Abstract: PURPOSE: To present and validate a self-supervised MRI reconstruction method that does not require fully sampled k-space data. METHODS: ReSiDe is inspired by plug-and-play (PnP) methods and employs a denoiser as a regularizer. In contrast to traditional PnP approaches that utilize generic denoisers or train deep learning-based denoisers using high-quality images or image patches, ReSiDe directly trains the denoiser on the image or images being reconstructed from the undersampled data. We introduce two variations of our method, ReSiDe-S and ReSiDe-M. ReSiDe-S is scan-specific and works with a single set of undersampled measurements, while ReSiDe-M operates on multiple sets of undersampled measurements. More importantly, the trained denoisers in ReSiDe-M are stored for PnP recovery without further training. To improve robustness, the denoising strength in ReSiDe-S and ReSiDe- M is auto-tuned using the discrepancy principle. RESULTS: Studies I, II, and III compare ReSiDe-S and ReSiDe-M against other self-supervised or unsupervised methods using data from T1- and T2-weighted brain MRI, MRXCAT digital perfusion phantom, and first-pass cardiac perfusion, respectively. ReSiDe-S and ReSiDe-M outperform other methods in terms of reconstruction signal-to-noise ratio and structural similarity index measure for Studies I and II and in terms of expert scoring for Study III. CONCLUSION: A self-supervised image reconstruction method is presented and validated in both static and dynamic MRI applications. These developments can benefit MRI applications where availability of fully sampled training data is limited.

Abstract: Under the global COVID-19 crisis, accurate diagnosis of COVID-19 from Chest X-ray (CXR) images is critical. To reduce intra- and inter-observer variability, during the radiological assessment, computer-aided diagnostic tools have been utilized to supplement medical decision-making and subsequent disease management. Computational methods with high accuracy and robustness are required for rapid triaging of patients and aiding radiologists in the interpretation of the collected data. In this study, we propose a novel multi-feature fusion network using parallel attention blocks to fuse the original CXR images and local-phase feature-enhanced CXR images at multi-scales. We examine our model on various COVID-19 datasets acquired from different organizations to assess the generalization ability. Our experiments demonstrate that our method achieves state-of-art performance and has improved generalization capability, which is crucial for widespread deployment.