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In vivo CRISPR-based screen identifies ZC3H12C as a mediator of CAR-T cell dysfunction in solid tumors

In vivo CRISPR-based screen identifies ZC3H12C...

Immunology
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librarian
1 view
Targeting ZC3H12C improves T cell persistence and antitumor function in adoptive T cell therapy

Targeting ZC3H12C improves T cell persistence ...

Immunology
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librarian
1 view
Mitochondrial uracil DNA glycosylase contributes to nuclear base excision repair

Mitochondrial uracil DNA glycosylase contribut...

Cell Biology
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librarian
3 views
Decoding the BRCA2 reversion principles underlying PARP inhibitor resistance

Decoding the BRCA2 reversion principles underl...

Cancer Biology
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librarian
4 views
Integrin-independent Tie2 activation using de novo designed proteins

Integrin-independent Tie2 activation using de ...

Biochemistry
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librarian
2 views
Post-GWAS functional annotation of the RPTOR locus identifies rs12950541 as a candidate regulatory variant for type 2 diabetes and metabolic traits

Post-GWAS functional annotation of the RPTOR l...

Genetics
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Hugo Gallardo Blanco
3 views
New Human IPSC Models of Late-onset Alzheimer's Disease Polygenic Risk Identify Multiple Impairments of Microglial Function

New Human IPSC Models of Late-onset Alzheimer'...

Neuroscience
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librarian
1 view
Neural priority maps encode behavioral relevance independently across multiple attended locations

Neural priority maps encode behavioral relevan...

Neuroscience
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librarian
2 views
Tuned inhibitory control of neuronal firing thresholds explains predictive sensorimotor behavior

Tuned inhibitory control of neuronal firing th...

Neuroscience
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librarian
2 views
DNA-induced conformational changes in SPRTN relieve its auto-inhibitory effect on protease activity

DNA-induced conformational changes in SPRTN re...

Biochemistry
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librarian
4 views
Foxp4+ Mandibular Skeletal Stem Cells Orchestrate Bone/Tooth Development and Regeneration

Foxp4+ Mandibular Skeletal Stem Cells Orchestr...

Cell Biology
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Rui Yue
3 views
The moonlighting functions of SEC13 in nonsense-mediated mRNA decay and the regulation of ER stress

The moonlighting functions of SEC13 in nonsens...

Molecular Biology
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librarian
5 views
A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE AND REPRESSIBLE VECTORS FOR FINE-TUNED GENE EXPRESSION

A VERSATILE LIBRARY OF TETRACYCLINE-INDUCIBLE ...

Synthetic Biology
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librarian
4 views
MNT loss in MYC-driven B lymphoma cells enhances apoptosis, inhibits proliferation and increases sensitivity to cancer drugs.

MNT loss in MYC-driven B lymphoma cells enhanc...

Cancer Biology
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Suzanne Cory
5 views
Rapid phylogenomic analysis for viral surveillance and metagenomic profiling with Omni2Tree

Rapid phylogenomic analysis for viral surveill...

Bioinformatics
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librarian
6 views
How Phosphorylation of How Phosphorylation of alpha/beta-Tubulin Perturbs Microtubule Structure: A Computational Study

How Phosphorylation of How Phosphorylation of ...

Biochemistry
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Susan Rotenberg
3 views
Discovery of Bordetella oligosaccharide - extracellular glycan common to genus Bordetella. Structure, immunogenicity and possible implications for host-pathogen interactions

Discovery of Bordetella oligosaccharide - extr...

Biochemistry
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librarian
3 views
Highly efficient genotype compression leveraging genealogical relatedness

Highly efficient genotype compression leveragi...

Genetics
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librarian
5 views
Repetitive DNA-resolved epigenomics maps chromatin rewiring during aging and malignant transformation

Repetitive DNA-resolved epigenomics maps chrom...

Molecular Biology
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librarian
6 views
Characterization of Cellular Senescence in Primary Human Astrocytes

Characterization of Cellular Senescence in Pri...

Molecular Biology
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librarian
6 views
Translational profiling uncovers a tonoplast sugar transporter essential for vascular system development and cell wall composition

Translational profiling uncovers a tonoplast s...

Plant Biology
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Rozenn Le Hir
9 views
Optimizing Lentiviral Vector-Based Delivery of SCN1A transgenes to Mammalian Cells

Optimizing Lentiviral Vector-Based Delivery of...

Synthetic Biology
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librarian
3 views
SpatialBench: Comparative cross-platform benchmarking of high-resolution spatial transcriptomics using matched mouse lymphoid tissue

SpatialBench: Comparative cross-platform bench...

Bioinformatics
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librarian
5 views
Bordetella oligosaccharide (BOS) is associated with lipopolysaccharide of Bordetella petrii - the ancestor-related species of the pathogenic Bordetella

Bordetella oligosaccharide (BOS) is associated...

Biochemistry
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librarian
3 views
Allosteric Logic Gate

Allosteric Logic Gate

Biophysics
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Davide Cois
5 views
Spanning-Tree Thermostatistics of Protein Allostery: An Exact Kirchhoff Framework with Application to Oncogenic KRAS

Spanning-Tree Thermostatistics of Protein Allo...

Biophysics
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librarian
5 views
Facilitating NMR Resonance Assignment with Metabolic Tampering

Facilitating NMR Resonance Assignment with Met...

Biochemistry
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J. Patrick Loria
3 views
Artificial intelligence aided design of peptides with custom secondary structure motifs and reduced amino acid alphabets

Artificial intelligence aided design of peptid...

Bioinformatics
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Scott Dean
6 views
Molecular mechanism of water and glycerol transport through hydrophobic selectivity filter in the aquaporin homolog of Trypanosoma brucei

Molecular mechanism of water and glycerol tran...

Biophysics
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Ramasubbu Sankararamakrishnan
3 views
Scan Cluster: A versatile database-independent prediction tool for multi-genome identification of homologous gene clusters.

Scan Cluster: A versatile database-independent...

Bioinformatics
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Mauricio Lozano
3 views
Phylogenomic Taxonomic Analysis of Ralstonia solanacearum Strains causing Bacterial Wilt Disease in Northeastern Argentina.

Phylogenomic Taxonomic Analysis of Ralstonia s...

Microbiology
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Alberto Gochez
3 views
Replication fork remodeling proteins, Smc5/6 and Rtt107, promote palindrome-mediated genome instability

Replication fork remodeling proteins, Smc5/6 a...

Molecular Biology
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Kirill Lobachev
5 views
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