Cancer Biology

FOXA1 preserves cell polarity and restrains lysosome biogenesis in non-small cell lung adenocarcinoma

FOXA1 preserves cell polarity and restrains ly...

Cancer Biology
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Jianxing He
6 views
Multi-region biopsies and patient-derived neurosphere cultures reveal spatial divergence in glioblastoma.

Multi-region biopsies and patient-derived neur...

Cancer Biology
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Franziska Michor
3 views
Transcriptomic, Genomic, and Clinical Characterization of Morphological Classes in Localized and Metastatic Pancreatic Cancer

Transcriptomic, Genomic, and Clinical Characte...

Cancer Biology
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librarian
5 views
KRAS inhibition is an effective therapy for appendiceal adenocarcinoma

KRAS inhibition is an effective therapy for ap...

Cancer Biology
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John Shen
9 views
The HPV E7 oncoprotein promotes LIM and SH3 Domain Protein 1 (LASP1) transcription via the Rb/E2F1 signalling pathway in HPV-positive cervical cancer cells

The HPV E7 oncoprotein promotes LIM and SH3 Do...

Cancer Biology
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librarian
5 views
Marker-based CRISPR screens identify POU2F1 as a regulator of DLL3 and neuroendocrine identity in small cell lung cancer

Marker-based CRISPR screens identify POU2F1 as...

Cancer Biology
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librarian
2 views
H3 dopaminylation and CaMKII modulate diffuse midline glioma response to CDK9 inhibition

H3 dopaminylation and CaMKII modulate diffuse ...

Cancer Biology
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librarian
2 views
Nanoparticle-delivered resiquimod induces brain tumor regression in medulloblastoma and diffuse midline glioma models by interrupting paracrine growth support and activating myeloid immune signaling and phagocytosis

Nanoparticle-delivered resiquimod induces brai...

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librarian
3 views
Myeloma and therapy reshape the bone marrow niche to durably constrain immune reconstitution and vaccine responsiveness

Myeloma and therapy reshape the bone marrow ni...

Cancer Biology
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librarian
3 views
Expression profile of CASSIOPEIA patients refines prognostic value of MRD negativity in multiple myeloma

Expression profile of CASSIOPEIA patients refi...

Cancer Biology
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librarian
7 views
A SIRT5-induced metabolic switch underlies chemoresistance and ATR checkpoint dependence in triple-negative breast cancer

A SIRT5-induced metabolic switch underlies che...

Cancer Biology
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librarian
5 views
RUNX1-deficiency drives immune-active ER+ mammary tumorigenesis through activation of interferon signaling

RUNX1-deficiency drives immune-active ER+ mamm...

Cancer Biology
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librarian
5 views
Integrating Fas-mediated apoptosis with IFNγ signaling to drive tumor regression in mRNA cancer therapeutics

Integrating Fas-mediated apoptosis with IFNγ s...

Cancer Biology
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librarian
4 views
A Hierarchical Spatial Graph Neural Network Resolves Immunogenic and Tolerogenic Tertiary Lymphoid Structures in Renal Cell Carcinoma

A Hierarchical Spatial Graph Neural Network Re...

Cancer Biology
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librarian
5 views
lncRNA MANCR isoforms selectively mediate multiple levels of epigenomic and P53-responsive transcriptional control in triple negative breast cancer

lncRNA MANCR isoforms selectively mediate mult...

Cancer Biology
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Janet Stein
6 views
Early Epigenetic and Metabolic Responses to the Adipocyte Secretome Reveal Stress-Adaptive States in Triple-Negative Breast Cancer

Early Epigenetic and Metabolic Responses to th...

Cancer Biology
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librarian
5 views
Serial Thermal Ablation Induces Abscopal Antitumor Immunity and Reveals Targetable CSF1R-Dependent Resistance in Pancreatic Cancer

Serial Thermal Ablation Induces Abscopal Antit...

Cancer Biology
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librarian
4 views
Transcription Factor Subtype Governs Response and Resistance to DLL3-Directed T-Cell Engagement in Small Cell Lung Cancer

Transcription Factor Subtype Governs Response ...

Cancer Biology
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librarian
12 views
Distinct Spatial Programs of Response versus Resistance in Non-Small Cell Lung Cancer after Neoadjuvant Chemoimmunotherapy

Distinct Spatial Programs of Response versus R...

Cancer Biology
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librarian
8 views
Defining the RNA Modification Landscape of Multiple Myeloma Reveals METTL3-Dependent m6A Regulation of NEAT1

Defining the RNA Modification Landscape of Mul...

Cancer Biology
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librarian
11 views
NFATC2 in pancreatic cancer-associated fibroblasts predicts treatment response and facilitates ERBB-targeted therapies

NFATC2 in pancreatic cancer-associated fibrobl...

Cancer Biology
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Biswajyoti Sahu
14 views
SPEND-hSRS imaging of fumarate uncovers mitochondrial metabolic heterogeneity

SPEND-hSRS imaging of fumarate uncovers mitoch...

Cancer Biology
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librarian
8 views
Combined inhibition of AIF/CHCHD4 interaction and GLS1 to exploit metabolic vulnerabilities in pediatric osteosarcoma

Combined inhibition of AIF/CHCHD4 interaction ...

Cancer Biology
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librarian
9 views
NG2-targeting macrophages inhibit 3D invasion of patient-derived glioblastoma spheroids

NG2-targeting macrophages inhibit 3D invasion ...

Cancer Biology
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librarian
7 views
Comparative single cell analysis of wound and cancer identifies the metabolic dialogues between tumor initiating stem cells and macrophages

Comparative single cell analysis of wound and ...

Cancer Biology
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librarian
8 views
Integrated analysis of stemness-associated immune modulatory circuits in squamous cell carcinomas

Integrated analysis of stemness-associated imm...

Cancer Biology
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Yuxuan Miao
11 views
Integrative Transcriptomic and Machine Learning Analysis of ecDNA-Associated Features for Studying Chemotherapy Resistance in TNBC

Integrative Transcriptomic and Machine Learnin...

Cancer Biology
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Dipongkor Saha
11 views
Sustained interferon exposure creates a hyper-metastatic subset of melanoma cells

Sustained interferon exposure creates a hyper-...

Cancer Biology
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Sean Morrison
16 views
Integrating Epstein-Barr virus (EBV) status into diffuse large B cell lymphoma (DLBCL) genetics

Integrating Epstein-Barr virus (EBV) status in...

Cancer Biology
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Eric Johannsen
17 views
Systemic and tumor intrinsic expansion of FCRL5 expressing B cells associates with poor response to Bacillus Calmette-Guerin immunotherapy in patients with non-muscle invasive bladder cancer

Systemic and tumor intrinsic expansion of FCRL...

Cancer Biology
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librarian
19 views
Inflammatory memory disables a DDR1 degradation checkpoint to enable pancreatic cancer growth

Inflammatory memory disables a DDR1 degradatio...

Cancer Biology
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Fei Yang
19 views
Quinolinic acid phosphoribosyl transferase moonlights as an apoptosis regulator to empower lung cancer progression

Quinolinic acid phosphoribosyl transferase moo...

Cancer Biology
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librarian
17 views
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