Cancer Biology

Decoding the BRCA2 reversion principles underlying PARP inhibitor resistance

Decoding the BRCA2 reversion principles underl...

Cancer Biology
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librarian
3 views
MNT loss in MYC-driven B lymphoma cells enhances apoptosis, inhibits proliferation and increases sensitivity to cancer drugs.

MNT loss in MYC-driven B lymphoma cells enhanc...

Cancer Biology
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Suzanne Cory
4 views
From Patient to Tumor Organoid: Culture Protocol Choice Controls Glioblastoma Tumor Architecture and Identity

From Patient to Tumor Organoid: Culture Protoc...

Cancer Biology
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Dasa Bohaciakova
8 views
Novel role of the lncRNA EPR as oncosuppressor in intestinal cancer.

Novel role of the lncRNA EPR as oncosuppressor...

Cancer Biology
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librarian
5 views
HF-125, a first-in-class computer-modeled novel inhibitor of Tribbles 2, for therapy of enzalutamide resistant, neuroendocrine prostate cancer.

HF-125, a first-in-class computer-modeled nove...

Cancer Biology
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Jagadananda Ghosh
8 views
Direct interaction between cancer cells and fibroblasts promotes early chemoresistance to standard-of-care drug therapy in small cell lung cancer (SCLC)

Direct interaction between cancer cells and fi...

Cancer Biology
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librarian
9 views
AI-based separation of malignant cell- and microenvironment-specific gene expression from bulk RNA sequencing enhances biomarker interpretation

AI-based separation of malignant cell- and mic...

Cancer Biology
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librarian
7 views
TEDEdb: a large-scale resource and multi-cohort analysis of transposable element differential expression in cancer

TEDEdb: a large-scale resource and multi-cohor...

Cancer Biology
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librarian
9 views
Small extracellular vesicular transfer of MYCN and glycolytic cargo coordinates metabolic and immunological reprogramming in neuroblastoma in vitro

Small extracellular vesicular transfer of MYCN...

Cancer Biology
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librarian
10 views
Systems serology of responses against tumor antigens in ovarian cancer reveal disrupted Fc-mediated immunity

Systems serology of responses against tumor an...

Cancer Biology
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librarian
13 views
Development of gemcitabine-modified miR-15a as a novel, multimodal treatment strategy to overcome 5-FU and oxaliplatin resistance in colorectal cancer

Development of gemcitabine-modified miR-15a as...

Cancer Biology
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Jingfang Ju
12 views
Diabetes Might Shape Vasculature, Tumor Dissemination and Circulating Inflammation Marker Profiles in Prostate Cancer.

Diabetes Might Shape Vasculature, Tumor Dissem...

Cancer Biology
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Natalia Bednarz-Knoll
14 views
Murine osteosarcoma recapitulates the driver landscape and genomic complexity of osteosarcoma evolution in humans

Murine osteosarcoma recapitulates the driver l...

Cancer Biology
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librarian
12 views
A SRC-Annexin A2 axis that couples membrane repair to microRNA export during radiation stress in glioblastoma

A SRC-Annexin A2 axis that couples membrane re...

Cancer Biology
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Gatikrushna Singh
16 views
Hepatocellular Carcinoma Revisited from Single Cell Sequencing: Dynamic Evolution from Epithelial Dedifferentiation to Mesenchymal Remodeling

Hepatocellular Carcinoma Revisited from Single...

Cancer Biology
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Kai Yan
11 views
Upregulation of PD-L1 as a putative mechanism of resistance to CD47 inhibition in non-small cell lung cancer

Upregulation of PD-L1 as a putative mechanism ...

Cancer Biology
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librarian
9 views
R8-Stabilized Multi-Epitope mRNA Vaccine Triggers Potent Intratumoral T Cell Infiltration and Suppresses Breast Cancer Progression.

R8-Stabilized Multi-Epitope mRNA Vaccine Trigg...

Cancer Biology
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librarian
11 views
SCIMETAR-seq tracks immunophenotype, demethylation, mutations, and transcriptomes in single cells undergoing HMA therapy

SCIMETAR-seq tracks immunophenotype, demethyla...

Cancer Biology
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Christopher Jolly
9 views
Metabolic and Anti-Proliferative Responses of Pancreatic Cancer Cells to Ultrasound and Nanobubble Treatment

Metabolic and Anti-Proliferative Responses of ...

Cancer Biology
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librarian
13 views
Microglial lipid signaling drives glioblastoma invasion and represents a therapeutic vulnerability

Microglial lipid signaling drives glioblastoma...

Cancer Biology
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librarian
16 views
Multi-level Analysis of Codon Usage Patterns Reveals Systematic Optimization of Oncogenic Gene Expression in Pancreatic Cancer

Multi-level Analysis of Codon Usage Patterns R...

Cancer Biology
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Lisa Müller
21 views
An Isoform-Centric, Structure-Aware Framework for Protein Function Prediction and Evaluation, Instantiated in 3DisoDeepPF

An Isoform-Centric, Structure-Aware Framework ...

Cancer Biology
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Xin Wang
18 views
Epigenetic and 3D Genome Changes Drive Primary Trastuzumab Resistance in HER2+ Breast Cancer

Epigenetic and 3D Genome Changes Drive Primary...

Cancer Biology
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librarian
18 views
Paired CRISPR screens identify mitochondrial metabolism and UBE2H as aneuploid-specific dependencies in human cancer cell lines

Paired CRISPR screens identify mitochondrial m...

Cancer Biology
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Klaske Schukken
10 views
Systemic delivery of CRISPR-Cas9 nickase suppresses oncogene amplified cancer progression

Systemic delivery of CRISPR-Cas9 nickase suppr...

Cancer Biology
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librarian
12 views
Site-Dependent Decoupling of Drug-Biomarker Associations in Clear Cell Renal Cell Carcinoma Revealed by Functional Profiling of Patient-Derived Cell Models

Site-Dependent Decoupling of Drug-Biomarker As...

Cancer Biology
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librarian
18 views
Tissue Memory Score measures transcriptional retention in solidtumors and predicts survival in clear cell renal cell carcinoma

Tissue Memory Score measures transcriptional r...

Cancer Biology
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librarian
21 views
Dual Pathways of Extracellular ATP Action in Cancer Cells: Purinergic Signaling Driven Senescence and Macropinocytic ATP Internalization

Dual Pathways of Extracellular ATP Action in C...

Cancer Biology
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librarian
19 views
Identification and SAR optimization of FBXO22-mediated TEAD Targeted Glue degraders

Identification and SAR optimization of FBXO22-...

Cancer Biology
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librarian
19 views
Single cell analysis reveals molecular traits of pediatric lymphoma resistant subclones

Single cell analysis reveals molecular traits ...

Cancer Biology
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Lisa Westerberg
15 views
Reprogramming of Lipid Metabolism by FLASH Radiotherapy Selectively Protects Radiosensitive Normal Tissues

Reprogramming of Lipid Metabolism by FLASH Rad...

Cancer Biology
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Shuhei Aramaki
13 views
Chromosome-arm-specific telomere length governs dual modes of structural genome evolution in IDH-mutant astrocytoma

Chromosome-arm-specific telomere length govern...

Cancer Biology
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librarian
15 views
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