Cancer Biology

Single cell Correlation Analysis (SCA): Identifying self-renewing subpopulation of human acute myeloid leukemia stem cells using single cell RNA sequencing analysis

Single cell Correlation Analysis (SCA): Identi...

Cancer Biology
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Zohar Sachs
2 views
mSWI/SNF complex inhibition sensitizes KRAS-mutant lung cancers to targeted therapies via epithelial-mesenchymal subversion

mSWI/SNF complex inhibition sensitizes KRAS-mu...

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Cigall Kadoch
2 views
Pancreatic cancer-associated organ dysfunction promotes muscle autophagy and contributes to peripheral tissue wasting

Pancreatic cancer-associated organ dysfunction...

Cancer Biology
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librarian
2 views
Spatially Integrated Multi-Omics reveals the Multicellular Landscape of Progenitor-Driven Glioblastoma Progression

Spatially Integrated Multi-Omics reveals the M...

Cancer Biology
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librarian
7 views
Next-generation all-in-one CRISPR/Cas9 multiply-edited CD30CAR-T cells:Potency despite risk of translocations

Next-generation all-in-one CRISPR/Cas9 multipl...

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librarian
5 views
A Comparison of Mechanisms Driving Lesion Outcomes during Lung Tumor and Tuberculosis Granuloma Formation

A Comparison of Mechanisms Driving Lesion Outc...

Cancer Biology
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librarian
6 views
Identifying Robust Subclonal Structures through Tumor Progression Tree Alignment

Identifying Robust Subclonal Structures throug...

Cancer Biology
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librarian
6 views
Anti-diabetic drug Repaglinide induces Apoptosis, Cell Cycle Arrest, and Inhibits Cell Migration in Human Breast and Lung Cancer Cells.

Anti-diabetic drug Repaglinide induces Apoptos...

Cancer Biology
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Govinda Rao Duddukuri
5 views
The vitamin K oxidoreductase VKORC1L1 prevents oxidative stress in hepatocytes and protects from MASLD and hepatocellular carcinoma

The vitamin K oxidoreductase VKORC1L1 prevents...

Cancer Biology
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Mathieu Ferron
7 views
Assessing the Operational Feasibility of Evolutionary Therapy in Metastatic Non-Small Cell Lung Cancer

Assessing the Operational Feasibility of Evolu...

Cancer Biology
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librarian
2 views
CKII-Phosphorylated HPV-16 E7 Disrupts Planar Cell Polarity by Recruiting Vangl1

CKII-Phosphorylated HPV-16 E7 Disrupts Planar ...

Cancer Biology
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Ifeoluwa Gbala
4 views
Inhibition of mucin-type O-glycosylation impairs melanogenesis, melanoma growth, and metastatic capacity

Inhibition of mucin-type O-glycosylation impai...

Cancer Biology
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Srinivasa-Gopalan Sampathkumar
22 views
Dissecting FOXA1 pioneering function by acute pharmacological degradation

Dissecting FOXA1 pioneering function by acute ...

Cancer Biology
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librarian
4 views
Domain-adaptation deep learning models do not outperform simple baseline models in single-cell anti-cancer drug sensitivity prediction

Domain-adaptation deep learning models do not ...

Cancer Biology
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Marina Esteban-Medina
8 views
Iron Metabolism as a Therapeutic Vulnerability in Stem Cell-Like Castration-Resistant Prostate Cancer

Iron Metabolism as a Therapeutic Vulnerability...

Cancer Biology
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librarian
9 views
Pharmacological targeting of EED is an effective therapeutic strategy in cellular models of incurable neuroendocrine prostate cancer

Pharmacological targeting of EED is an effecti...

Cancer Biology
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Kayleigh Orchard
9 views
Leukemia stem cell expansion cultures reveal clonal drivers of leukemogenesis and therapy response

Leukemia stem cell expansion cultures reveal c...

Cancer Biology
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librarian
7 views
Benzoxaboroles are structurally unique binders of eukaryotic translation initiation factor 4E

Benzoxaboroles are structurally unique binders...

Cancer Biology
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librarian
8 views
Myc inhibition triggers GM-CSF-driven regression of pancreatic tumours

Myc inhibition triggers GM-CSF-driven regressi...

Cancer Biology
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librarian
13 views
A Developmental Lectin-Glycan Program Enables Early Breast Cancer Dissemination and Metastatic Onset

A Developmental Lectin-Glycan Program Enables ...

Cancer Biology
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Mariana Salatino
11 views
AID Shapes Proliferation and Cell-of-Origin-associated Transcriptional Programs in Diffuse Large B-cell Lymphoma

AID Shapes Proliferation and Cell-of-Origin-as...

Cancer Biology
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librarian
10 views
ACB1801 enhances tumor immunogenicity by targeting glycolysis/ferroptosis vulnerability and activating STAT1-signaling to overcome anti-PD-1 resistance in MSS colorectal cancer

ACB1801 enhances tumor immunogenicity by targe...

Cancer Biology
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Bassam Janji
8 views
Local Tumor Microenvironment Niches Correlate With Survival And Immunotherapy Response In Human Glioblastoma

Local Tumor Microenvironment Niches Correlate ...

Cancer Biology
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librarian
12 views
Retrotransposons Promote Clonal Hematopoiesis Through Aging-Related Stromal Inflammation

Retrotransposons Promote Clonal Hematopoiesis ...

Cancer Biology
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librarian
13 views
Convergence on BRAF and MAPK Signaling in Glioma Development in a P53-ENU model

Convergence on BRAF and MAPK Signaling in Glio...

Cancer Biology
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librarian
13 views
Overcoming Cisplatin Resistance in 3D Oral Squamous Cell Carcinoma Models via Nanoparticle-Mediated Pt(IV) Drug Delivery.

Overcoming Cisplatin Resistance in 3D Oral Squ...

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librarian
11 views
eIF4E and Ezrin cooperate in pseudopods to drive a localized migratory translation program in acute myeloid leukemia

eIF4E and Ezrin cooperate in pseudopods to dri...

Cancer Biology
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Katherine Borden
12 views
Quantitative dissection of the metastatic cascade at single colony resolution

Quantitative dissection of the metastatic casc...

Cancer Biology
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Rui Tang
14 views
Mega-frequency mutagenesis: generation of non-random precise mutations with extremely high frequency upon adaptation of cancer cells to drugs and stress

Mega-frequency mutagenesis: generation of non-...

Cancer Biology
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Victor Oleynik
7 views
Predictable clonal hierarchies from restricted progenitors provide a framework for cell type-specific therapies in glioblastoma

Predictable clonal hierarchies from restricted...

Cancer Biology
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librarian
27 views
NRF2 pathway activation and SPP1⁺TREM2⁺ macrophages drive chemoradiotherapy resistance in esophageal squamous cell carcinoma

NRF2 pathway activation and SPP1⁺TREM2⁺ macrop...

Cancer Biology
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Kuaile Zhao
14 views
Cholesterol Biosynthesis is a Targetable Vulnerability of CEBPA-mutant Acute Myeloid Leukemia

Cholesterol Biosynthesis is a Targetable Vulne...

Cancer Biology
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librarian
12 views
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