Biochemistry

Engineered Cas9 complexes establish an experimentally grounded benchmark for heterogeneous cryoEM reconstruction methods

Engineered Cas9 complexes establish an experim...

Biochemistry
Avatar
librarian
2 views
Evolutionarily Conserved Amyloid Aggregation in the PACAP Peptide Family Is Controlled by Heparin-Sensitive Lys/Arg Gatekeeper Residues

Evolutionarily Conserved Amyloid Aggregation i...

Biochemistry
Avatar
András Perczel
3 views
Multi-state Ensemble Refinement for Occupancy Statistics (MEROS) in Time-Resolved X-ray Crystallography

Multi-state Ensemble Refinement for Occupancy ...

Biochemistry
Avatar
librarian
4 views
Computational design of membrane fusion proteins

Computational design of membrane fusion proteins

Biochemistry
Avatar
librarian
4 views
Rewiring c-Myc Transcriptional Activity with an O-GlcNAcylation Targeting Chimera (OGTAC)

Rewiring c-Myc Transcriptional Activity with a...

Biochemistry
Avatar
librarian
4 views
Site-specific phosphorylation of Ser352 drives aggregation of Tau R4 under acidosis conditions

Site-specific phosphorylation of Ser352 drives...

Biochemistry
Avatar
librarian
5 views
ARHGEF7 S-glutathionylation promotes cancer cell migration through Rac1 activation

ARHGEF7 S-glutathionylation promotes cancer ce...

Biochemistry
Avatar
Young-Hoon Ahn
8 views
COSMIC-Linked Ras Mutations at the Interface Between H-Ras and PI3KγRBD Frequently Generate Affinity Increases as Well as Affinity Decreases

COSMIC-Linked Ras Mutations at the Interface B...

Biochemistry
Avatar
librarian
6 views
Metabolic glues as a means of purine sensing and chemotherapeutic response

Metabolic glues as a means of purine sensing a...

Biochemistry
Avatar
librarian
8 views
Methionine, Not S-adenosylmethionine, Acts as a Primary Metabolic Stress Signal for Chromatin Remodeling

Methionine, Not S-adenosylmethionine, Acts as ...

Biochemistry
Avatar
John Denu
7 views
Resolving hidden stoichiometries in Bacterial proteasome activator (Bpa)-substrate complexes by cryo-EM and charge detection mass spectrometry

Resolving hidden stoichiometries in Bacterial ...

Biochemistry
Avatar
librarian
5 views
TIR-like NADases act in bacterial immunity and the RNA vault

TIR-like NADases act in bacterial immunity and...

Biochemistry
Avatar
librarian
7 views
Exploration of targeted electrophilic kinase probes identifies a covalent ULK1 degrader

Exploration of targeted electrophilic kinase p...

Biochemistry
Avatar
librarian
7 views
Top-down Sequencing of Intact Proteoforms using the timsOmni mass spectrometer: Accurate Determination of Co-occurring Histone Modifications

Top-down Sequencing of Intact Proteoforms usin...

Biochemistry
Avatar
Ole Jensen
7 views
A Python Dash App and cPanel workflow to automate metabolomics data analyses and visualisation

A Python Dash App and cPanel workflow to autom...

Biochemistry
Avatar
librarian
8 views
Synthesis and evaluation of novel copper-antibody conjugates for the chemodynamic therapy of HER2-positive breast cancer

Synthesis and evaluation of novel copper-antib...

Biochemistry
Avatar
librarian
11 views
Computational modeling of pro-inflammatory cytokine-enhanced blood coagulation

Computational modeling of pro-inflammatory cyt...

Biochemistry
Avatar
librarian
12 views
Efficient co-transcriptional splicing enforces rapid microexon definition and inclusion by SRRM4

Efficient co-transcriptional splicing enforces...

Biochemistry
Avatar
librarian
15 views
Nonequilibrium States Promote One-Pot Nonenzymatic Carbon Fixation in the Reverse Tricarboxylic Acid Cycle and Amino Acid Synthesis

Nonequilibrium States Promote One-Pot Nonenzym...

Biochemistry
Avatar
librarian
14 views
Differences in substrate engagement and Retinoblastoma protein (RB) binding of human KDM5A and KDM5B

Differences in substrate engagement and Retino...

Biochemistry
Avatar
Simon Poepsel
18 views
Structural Insights into the Coupling Mechanism of Vectorial CO2 Uptake by DAB1

Structural Insights into the Coupling Mechanis...

Biochemistry
Avatar
David Savage
18 views
Bipartite DNA binding domain of transcription factor BCL11B binds clustered short DNA sequence motifs

Bipartite DNA binding domain of transcription ...

Biochemistry
Avatar
librarian
20 views
Integrin-independent Tie2 activation using de novo designed proteins

Integrin-independent Tie2 activation using de ...

Biochemistry
Avatar
librarian
22 views
DNA-induced conformational changes in SPRTN relieve its auto-inhibitory effect on protease activity

DNA-induced conformational changes in SPRTN re...

Biochemistry
Avatar
librarian
22 views
How Phosphorylation of How Phosphorylation of alpha/beta-Tubulin Perturbs Microtubule Structure: A Computational Study

How Phosphorylation of How Phosphorylation of ...

Biochemistry
Avatar
Susan Rotenberg
22 views
Discovery of Bordetella oligosaccharide - extracellular glycan common to genus Bordetella. Structure, immunogenicity and possible implications for host-pathogen interactions

Discovery of Bordetella oligosaccharide - extr...

Biochemistry
Avatar
librarian
20 views
Bordetella oligosaccharide (BOS) is associated with lipopolysaccharide of Bordetella petrii - the ancestor-related species of the pathogenic Bordetella

Bordetella oligosaccharide (BOS) is associated...

Biochemistry
Avatar
librarian
22 views
Facilitating NMR Resonance Assignment with Metabolic Tampering

Facilitating NMR Resonance Assignment with Met...

Biochemistry
Avatar
J. Patrick Loria
21 views
Characterizing the effect of short wavelengths on the floral flavonoid metabolome of medicinal cannabis using a comparative computational metabolomics workflow

Characterizing the effect of short wavelengths...

Biochemistry
Avatar
librarian
19 views
Identification of key Y4R residues enables the discovery of selective non-peptide small-molecule agonists

Identification of key Y4R residues enables the...

Biochemistry
Avatar
librarian
24 views
Improved sensors for fructose-1,6-bisphosphate enable in vivo imaging of glycolysis

Improved sensors for fructose-1,6-bisphosphate...

Biochemistry
Avatar
librarian
19 views
Isolation and In vitro Characterization of BchE, the Cobalamin-Dependent Anaerobic Magnesium Protoporphyrin IX Monomethylester Cyclase Involved in Bacteriochlorophyll Biosynthesis

Isolation and In vitro Characterization of Bch...

Biochemistry
Avatar
librarian
19 views
Load more