Biochemistry

Redesign of energetically frustrated regions rescues function in defective T4 clamp loaders

Redesign of energetically frustrated regions r...

Biochemistry
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librarian
2 views
Substrate-dependent crosslinking by the cytochrome P450 from aminopyruvatide biosynthesis

Substrate-dependent crosslinking by the cytoch...

Biochemistry
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librarian
1 view
Context-dependent peptide recognition shapes tyrosine kinase substrate specificity beyond consensus motifs

Context-dependent peptide recognition shapes t...

Biochemistry
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Jerome Fox
2 views
Conformational Diversity and Substrate Specificity are Decoupled in Ancestral and Extant Glucokinases

Conformational Diversity and Substrate Specifi...

Biochemistry
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librarian
2 views
Heterogeneous reconstruction algorithms for cryoEM achieve limited particle classification accuracy on real benchmark datasets

Heterogeneous reconstruction algorithms for cr...

Biochemistry
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Laurel Kinman
2 views
dCas9 metabolic enzyme fusions modulate global and locus specific gene expression

dCas9 metabolic enzyme fusions modulate global...

Biochemistry
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librarian
7 views
Linking the kinetic mechanism to structural dynamics required for nucleotide hydrolysis by an alphavirus nsP2 RNA helicase

Linking the kinetic mechanism to structural dy...

Biochemistry
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librarian
7 views
Structural Co-optation and Loss-of-function Underlie the Evolution of Regulatory Novelty in the Glucokinase Regulatory Protein

Structural Co-optation and Loss-of-function Un...

Biochemistry
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librarian
5 views
AAV2 Crosslinks Actin Filaments: Implications for AAV Gene Therapy Vector Design

AAV2 Crosslinks Actin Filaments: Implications ...

Biochemistry
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librarian
5 views
Molecular architecture of meiotic pro-crossover factor HEI10 reveals coupling of higher-order assembly and ubiquitin chain formation

Molecular architecture of meiotic pro-crossove...

Biochemistry
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librarian
7 views
Molecular basis for the role of Ripr in Plasmodium falciparum invasion of human erythrocytes

Molecular basis for the role of Ripr in Plasmo...

Biochemistry
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Stephen Scally
6 views
Localized heme sensing through a ternary molecular glue

Localized heme sensing through a ternary molec...

Biochemistry
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librarian
13 views
A de novo CO2 Reductase Featuring a Cysteine-Ligated Cobalt Porphyrin Cofactor

A de novo CO2 Reductase Featuring a Cysteine-L...

Biochemistry
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librarian
16 views
The development of ToF-SIMS for in-situ glycosaminoglycan analysis

The development of ToF-SIMS for in-situ glycos...

Biochemistry
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librarian
9 views
Hydrophobic pocket engineering of arylmalonate decarboxylase expands its substrate scope towards the synthesis of the (R)-enantiomers of sterically hindered carboxylic acids

Hydrophobic pocket engineering of arylmalonate...

Biochemistry
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librarian
9 views
The turn less taken: Investigating patterns in β-turn dynamics using large-scale molecular dynamics data

The turn less taken: Investigating patterns in...

Biochemistry
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librarian
9 views
A CYFIP1-Inspired Peptidomimetic Modulates eIF4E-Dependent Translational Control in Cancer and Neurodevelopmental Disorders

A CYFIP1-Inspired Peptidomimetic Modulates eIF...

Biochemistry
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Alice Romagnoli
12 views
Rhodopsin is a tunable capacitor buffering the toxic, desensitizing retinoids of the vertebrate eye

Rhodopsin is a tunable capacitor buffering the...

Biochemistry
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Gianni Castiglione
9 views
LonP1 chaperone-like activity is ATPase independent and is mediated by its N-domain

LonP1 chaperone-like activity is ATPase indepe...

Biochemistry
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librarian
9 views
Schizokinen siderophores in the methylotrophy model organism Methylorubrum extorquens AM1

Schizokinen siderophores in the methylotrophy ...

Biochemistry
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librarian
8 views
Ethanol-assisted core-shell microparticles for enzyme stabilization with precise size control

Ethanol-assisted core-shell microparticles for...

Biochemistry
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librarian
9 views
Assessing State-Specific Accuracy of Cofolding Models for Kinases and GPCRs

Assessing State-Specific Accuracy of Cofolding...

Biochemistry
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Petra Knaus
10 views
Systematic Characterization of Thermal Stability Assay Parameters and Application in Discovery of Peptide-Protein Interactions

Systematic Characterization of Thermal Stabili...

Biochemistry
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librarian
8 views
Multi-Substrate Specificity of Isoflavone hydroxylases (GmIFH) Drive Isoflavonoid Diversification in Soybean

Multi-Substrate Specificity of Isoflavone hydr...

Biochemistry
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librarian
9 views
Stable isotope-assisted computational mass spectrometry reveals root-specific alkaloids in Glycyrrhiza species

Stable isotope-assisted computational mass spe...

Biochemistry
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Hiroshi Tsugawa
8 views
A method to synthesize analytical rhodoquinone standards for quantitative analysis in tissue specimen

A method to synthesize analytical rhodoquinone...

Biochemistry
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Akbar Ali
12 views
Precision Aptamers Against a Native GPCR through Ligand-Guided Selection

Precision Aptamers Against a Native GPCR throu...

Biochemistry
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librarian
14 views
Gating Mechanism of the Human Connexin 45 Gap Junction Channel

Gating Mechanism of the Human Connexin 45 Gap ...

Biochemistry
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librarian
14 views
DRUG TARGET IDENTIFICATION VIA A CONDITIONALLY STABILIZED TurboID ENZYME

DRUG TARGET IDENTIFICATION VIA A CONDITIONALLY...

Biochemistry
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librarian
13 views
Engineered Cas9 complexes establish an experimentally grounded benchmark for heterogeneous cryoEM reconstruction methods

Engineered Cas9 complexes establish an experim...

Biochemistry
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librarian
13 views
Evolutionarily Conserved Amyloid Aggregation in the PACAP Peptide Family Is Controlled by Heparin-Sensitive Lys/Arg Gatekeeper Residues

Evolutionarily Conserved Amyloid Aggregation i...

Biochemistry
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András Perczel
14 views
Multi-state Ensemble Refinement for Occupancy Statistics (MEROS) in Time-Resolved X-ray Crystallography

Multi-state Ensemble Refinement for Occupancy ...

Biochemistry
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librarian
17 views
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