Biochemistry

DNA Ligases Discriminate Between Natural and Non-Natural Base Pairs

DNA Ligases Discriminate Between Natural and N...

Biochemistry
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Adele Williamson
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A discrete-to-continuous mathematical model for ensemble distributions of a ligand-interacting macromolecular species across milieux-dependent conformational states may offer insights into the genesis and progression of cooperative binding

A discrete-to-continuous mathematical model fo...

Biochemistry
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librarian
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Distinct roles of three trypanosomal Oxa1 insertases in biogenesis of mitochondrial membrane complexes

Distinct roles of three trypanosomal Oxa1 inse...

Biochemistry
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librarian
1 view
Rhizobial enzyme reveals pH-driven catalytic switching and ʟ-amino acid incorporation by ʟ,-transpeptidases

Rhizobial enzyme reveals pH-driven catalytic s...

Biochemistry
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librarian
1 view
Sortase-mediated enrichment of ubiquitinated proteins from complex samples

Sortase-mediated enrichment of ubiquitinated p...

Biochemistry
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librarian
1 view
Ontological Analysis of Brain Proteostasis Highlights the Sex-Dependent Trajectory of ApoE Isoform-Specific Regulation

Ontological Analysis of Brain Proteostasis Hig...

Biochemistry
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librarian
1 view
Intact and single-molecule analysis of heparan sulfate

Intact and single-molecule analysis of heparan...

Biochemistry
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librarian
5 views
Selective knockout of PKA regulatory subunits reveal opposite catalytic and metabolic consequences with implications for Alzheimer's disease

Selective knockout of PKA regulatory subunits ...

Biochemistry
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librarian
4 views
Genetic Code Expansion for Site-Specific Encoding of a Switchable, Intrinsic Fluorophore-Quencher Pair to Monitor Protein Dynamics

Genetic Code Expansion for Site-Specific Encod...

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librarian
7 views
Where do the ligands bind? Co-folding bitter taste GPCRs with the BitterDB chemical space

Where do the ligands bind? Co-folding bitter t...

Biochemistry
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librarian
8 views
Systematic optimization and benchmarking of synchro-PASEF for high-throughput phosphoproteome profiling

Systematic optimization and benchmarking of sy...

Biochemistry
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librarian
7 views
Antiglycation effects of imidazole dipeptides and 2-oxo-imidazole dipeptides on glyceraldehyde-induced intracellular protein glycation and neuronal cell death

Antiglycation effects of imidazole dipeptides ...

Biochemistry
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librarian
16 views
Expanding the methionine toolkit: L-cyanohomoalanine as a multifunctional analog

Expanding the methionine toolkit: L-cyanohomoa...

Biochemistry
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librarian
19 views
Hydration and H/D exchange-dependent infrared signatures of the GCN4 leucine zipper

Hydration and H/D exchange-dependent infrared ...

Biochemistry
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librarian
14 views
Small-molecule inhibition of the Orientia tsutsugamushi deubiquitylating enzyme OtDUB impairs bacterial reproduction

Small-molecule inhibition of the Orientia tsut...

Biochemistry
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librarian
19 views
Hot Pursuit: Bioinformatic and Biochemical Characterization of a Hyperthermophilic Family B DNA Polymerase from Pyrolobus fumarii A1

Hot Pursuit: Bioinformatic and Biochemical Cha...

Biochemistry
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Wojciech Rusinek
15 views
Self-assembling nanoparticles to assess multivalent interactions between influenza A virus hemagglutinin and glycan surfaces

Self-assembling nanoparticles to assess multiv...

Biochemistry
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librarian
20 views
Development and Analytical Validation of a Smartphone-Based Quantitative Lateral Flow Immunoassay for Serum Cystatin-C

Development and Analytical Validation of a Sma...

Biochemistry
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librarian
24 views
Ancient origins of alkaloid biosynthesis in medicinal clubmosses

Ancient origins of alkaloid biosynthesis in me...

Biochemistry
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Ryan Nett
22 views
Discovery of CDK4-selective molecular glue degraders by high-throughput proteomics

Discovery of CDK4-selective molecular glue deg...

Biochemistry
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Henrik Daub
16 views
Near-Infrared Turn-On Fluorogenic Probe for Versatile Detection of Inorganic Polyphosphates

Near-Infrared Turn-On Fluorogenic Probe for Ve...

Biochemistry
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Rūta Gerasimaitė
17 views
Capturing early events in aryl hydrocarbon receptor activation using two complementary protein-protein interaction assays

Capturing early events in aryl hydrocarbon rec...

Biochemistry
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librarian
16 views
Nucleotide-driven KaiC dynamics coordinate the core properties of the cyanobacterial circadian clock

Nucleotide-driven KaiC dynamics coordinate the...

Biochemistry
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librarian
20 views
Design and discovery of "tug-of-war" riboswitches

Design and discovery of "tug-of-war" riboswitches

Biochemistry
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librarian
34 views
Discovery of cell-active small molecule inhibitors of UDP-galactose 4'-epimerase

Discovery of cell-active small molecule inhibi...

Biochemistry
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Michael Boyce
37 views
Enzyme-Linked Cycloaddition Assay (ELCA) for rapid, ultra-sensitive monitoring of secreted sialoglycoproteins

Enzyme-Linked Cycloaddition Assay (ELCA) for r...

Biochemistry
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librarian
32 views
Hepatocyte-, but not myeloid cell-Rictor/mTORC2 deficiency moderately attenuates steatotic liver disease induced by intake of a choline-deficient, amino acid-defined high-fat diet

Hepatocyte-, but not myeloid cell-Rictor/mTORC...

Biochemistry
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librarian
27 views
Systemic degradation of repressive transcription factors gates gene expression and cell fate specification

Systemic degradation of repressive transcripti...

Biochemistry
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librarian
24 views
RNA 3D Motif Dynamics Guide Assembly of the Replication Initiation Complex in Flaviviruses

RNA 3D Motif Dynamics Guide Assembly of the Re...

Biochemistry
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Steve Bonilla
28 views
Human ASPDH is a 2-aminomuconate reductase that produces L-2-aminohex-3-enedioic acid in tryptophan catabolism

Human ASPDH is a 2-aminomuconate reductase tha...

Biochemistry
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riccardo percudani
33 views
A multifunctional polyketide synthase in nematodes produces divergent families of signaling molecules that control different developmental arrests

A multifunctional polyketide synthase in nemat...

Biochemistry
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librarian
92 views
Structural Characterization of Calcium-Dependent Calmodulin-Calmidazolium Binding using Capillary Vibrating Sharp-Edge Spray-based Native Mass Spectrometry and In-Droplet Hydrogen Deuterium Exchange Mass Spectrometry

Structural Characterization of Calcium-Depende...

Biochemistry
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librarian
90 views
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