Biochemistry

Where do the ligands bind? Co-folding bitter taste GPCRs with the BitterDB chemical space

Where do the ligands bind? Co-folding bitter t...

Biochemistry
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librarian
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Systematic optimization and benchmarking of synchro-PASEF for high-throughput phosphoproteome profiling

Systematic optimization and benchmarking of sy...

Biochemistry
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librarian
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Antiglycation effects of imidazole dipeptides and 2-oxo-imidazole dipeptides on glyceraldehyde-induced intracellular protein glycation and neuronal cell death

Antiglycation effects of imidazole dipeptides ...

Biochemistry
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librarian
7 views
Expanding the methionine toolkit: L-cyanohomoalanine as a multifunctional analog

Expanding the methionine toolkit: L-cyanohomoa...

Biochemistry
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librarian
9 views
Hydration and H/D exchange-dependent infrared signatures of the GCN4 leucine zipper

Hydration and H/D exchange-dependent infrared ...

Biochemistry
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librarian
6 views
Small-molecule inhibition of the Orientia tsutsugamushi deubiquitylating enzyme OtDUB impairs bacterial reproduction

Small-molecule inhibition of the Orientia tsut...

Biochemistry
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librarian
8 views
Hot Pursuit: Bioinformatic and Biochemical Characterization of a Hyperthermophilic Family B DNA Polymerase from Pyrolobus fumarii A1

Hot Pursuit: Bioinformatic and Biochemical Cha...

Biochemistry
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Wojciech Rusinek
8 views
Self-assembling nanoparticles to assess multivalent interactions between influenza A virus hemagglutinin and glycan surfaces

Self-assembling nanoparticles to assess multiv...

Biochemistry
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librarian
11 views
Development and Analytical Validation of a Smartphone-Based Quantitative Lateral Flow Immunoassay for Serum Cystatin-C

Development and Analytical Validation of a Sma...

Biochemistry
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librarian
18 views
Ancient origins of alkaloid biosynthesis in medicinal clubmosses

Ancient origins of alkaloid biosynthesis in me...

Biochemistry
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Ryan Nett
18 views
Discovery of CDK4-selective molecular glue degraders by high-throughput proteomics

Discovery of CDK4-selective molecular glue deg...

Biochemistry
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Henrik Daub
14 views
Near-Infrared Turn-On Fluorogenic Probe for Versatile Detection of Inorganic Polyphosphates

Near-Infrared Turn-On Fluorogenic Probe for Ve...

Biochemistry
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Rūta Gerasimaitė
14 views
Capturing early events in aryl hydrocarbon receptor activation using two complementary protein-protein interaction assays

Capturing early events in aryl hydrocarbon rec...

Biochemistry
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librarian
13 views
Nucleotide-driven KaiC dynamics coordinate the core properties of the cyanobacterial circadian clock

Nucleotide-driven KaiC dynamics coordinate the...

Biochemistry
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librarian
18 views
Design and discovery of "tug-of-war" riboswitches

Design and discovery of "tug-of-war" riboswitches

Biochemistry
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librarian
31 views
Discovery of cell-active small molecule inhibitors of UDP-galactose 4'-epimerase

Discovery of cell-active small molecule inhibi...

Biochemistry
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Michael Boyce
33 views
Enzyme-Linked Cycloaddition Assay (ELCA) for rapid, ultra-sensitive monitoring of secreted sialoglycoproteins

Enzyme-Linked Cycloaddition Assay (ELCA) for r...

Biochemistry
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librarian
29 views
Hepatocyte-, but not myeloid cell-Rictor/mTORC2 deficiency moderately attenuates steatotic liver disease induced by intake of a choline-deficient, amino acid-defined high-fat diet

Hepatocyte-, but not myeloid cell-Rictor/mTORC...

Biochemistry
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librarian
25 views
Systemic degradation of repressive transcription factors gates gene expression and cell fate specification

Systemic degradation of repressive transcripti...

Biochemistry
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librarian
21 views
RNA 3D Motif Dynamics Guide Assembly of the Replication Initiation Complex in Flaviviruses

RNA 3D Motif Dynamics Guide Assembly of the Re...

Biochemistry
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Steve Bonilla
26 views
Human ASPDH is a 2-aminomuconate reductase that produces L-2-aminohex-3-enedioic acid in tryptophan catabolism

Human ASPDH is a 2-aminomuconate reductase tha...

Biochemistry
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riccardo percudani
32 views
A multifunctional polyketide synthase in nematodes produces divergent families of signaling molecules that control different developmental arrests

A multifunctional polyketide synthase in nemat...

Biochemistry
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librarian
91 views
Structural Characterization of Calcium-Dependent Calmodulin-Calmidazolium Binding using Capillary Vibrating Sharp-Edge Spray-based Native Mass Spectrometry and In-Droplet Hydrogen Deuterium Exchange Mass Spectrometry

Structural Characterization of Calcium-Depende...

Biochemistry
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librarian
85 views
Reparameterization of the Amber RNA Force Field Non-Bonded Terms

Reparameterization of the Amber RNA Force Fiel...

Biochemistry
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librarian
85 views
Cholesterol links blood feeding to mosquito development and reproduction

Cholesterol links blood feeding to mosquito de...

Biochemistry
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Yoram Gerchman
71 views
Disease-associated mutations in TPM2 alter regulation of actin filament stability and cofilin-dependent dynamics

Disease-associated mutations in TPM2 alter reg...

Biochemistry
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Joanna Moraczewska
69 views
Structure of the human HIRA histone chaperone with a nucleosome suggests a stepwise nucleosome assembly mechanism

Structure of the human HIRA histone chaperone ...

Biochemistry
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librarian
68 views
Mcm10 braces converging replicative helicases to pull apart origin DNA

Mcm10 braces converging replicative helicases ...

Biochemistry
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librarian
74 views
Evolution of allostery without shape shifting: Internal dynamics drives functional diversification of a transcriptional repressor superfamily

Evolution of allostery without shape shifting:...

Biochemistry
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librarian
57 views
Symmetry Analysis and Ancestral Sequence Reconstruction Reveal a Symmetrical Translocation Pathway and Activity Determinants of ZIP Metal Transporter

Symmetry Analysis and Ancestral Sequence Recon...

Biochemistry
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librarian
61 views
Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase

Potent reaction hijacking inhibitors of Plasmo...

Biochemistry
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Miles Siegel
58 views
Structure and inhibition of the sperm TMEM95-FIMP complex in mammalian fertilization

Structure and inhibition of the sperm TMEM95-F...

Biochemistry
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Shaogeng Tang
78 views
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