Biochemistry

Mcm10 braces converging replicative helicases to pull apart origin DNA

Mcm10 braces converging replicative helicases ...

Biochemistry
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librarian
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Evolution of allostery without shape shifting: Internal dynamics drives functional diversification of a transcriptional repressor superfamily

Evolution of allostery without shape shifting:...

Biochemistry
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librarian
3 views
Symmetry Analysis and Ancestral Sequence Reconstruction Reveal a Symmetrical Translocation Pathway and Activity Determinants of ZIP Metal Transporter

Symmetry Analysis and Ancestral Sequence Recon...

Biochemistry
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librarian
8 views
Potent reaction hijacking inhibitors of Plasmodium falciparum asparagine tRNA synthetase

Potent reaction hijacking inhibitors of Plasmo...

Biochemistry
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Miles Siegel
7 views
Structure and inhibition of the sperm TMEM95-FIMP complex in mammalian fertilization

Structure and inhibition of the sperm TMEM95-F...

Biochemistry
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Shaogeng Tang
6 views
Mouse Fc-FcγRIV structure guides Fc engineering for cross-species FcγR recognition

Mouse Fc-FcγRIV structure guides Fc engineerin...

Biochemistry
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librarian
6 views
Hsp10: From Single to Double Rings-Structural Basis of Protein Homeostasis

Hsp10: From Single to Double Rings-Structural ...

Biochemistry
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librarian
7 views
Small-molecule modulators of HIPK4 activity and proteostasis

Small-molecule modulators of HIPK4 activity an...

Biochemistry
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Thomas Chung
7 views
Mass spectrometric analysis of free methionine oxidation levels in E. coli

Mass spectrometric analysis of free methionine...

Biochemistry
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librarian
4 views
Structure and Mechanism of a Two-component Lanthipeptide Toxin

Structure and Mechanism of a Two-component Lan...

Biochemistry
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Ryan Moreira
5 views
A nested shell structure coordinates enzyme communication in pyruvate oxidation

A nested shell structure coordinates enzyme co...

Biochemistry
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librarian
5 views
OptiFoot: a method for recording protein footprints on DNA for microscopy and sequence analysis

OptiFoot: a method for recording protein footp...

Biochemistry
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librarian
8 views
Dual-Lipa: A sequential multi-omic subcellular landscape map of mouse heart

Dual-Lipa: A sequential multi-omic subcellular...

Biochemistry
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librarian
8 views
PARG activity is required for cell death by parthanatos

PARG activity is required for cell death by pa...

Biochemistry
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librarian
7 views
Phytochemical profiling and antioxidant potential of freshwater algal extracts from Lahore, Pakistan, with preliminary evaluation of cytotoxic activity

Phytochemical profiling and antioxidant potent...

Biochemistry
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librarian
5 views
Structural basis for Ca2+-dependent, RyR2-selective stabilization by Ryanozole in CPVT

Structural basis for Ca2+-dependent, RyR2-sele...

Biochemistry
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librarian
7 views
Substrate-derived peptides for selective covalent inhibition of protein tyrosine kinases

Substrate-derived peptides for selective coval...

Biochemistry
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librarian
6 views
Biophysical and enzymatic comparison of Bacillus safensis and Bacillus subtilis malate dehydrogenase (MDH) enzymes

Biophysical and enzymatic comparison of Bacill...

Biochemistry
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librarian
6 views
Iterative structural homology search identifies new substrates of the protein O-fucosyltransferases POFUT3 and POFUT4

Iterative structural homology search identifie...

Biochemistry
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librarian
7 views
dsRADAR: Imaging and Quantifying Cellular dsRNA by Repurposing RNA Binding Proteins

dsRADAR: Imaging and Quantifying Cellular dsRN...

Biochemistry
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Jennifer Heemstra
6 views
Structural and kinetic insights into a metagenomics-derived Cas12a with high specificity

Structural and kinetic insights into a metagen...

Biochemistry
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Tyler Dangerfield
8 views
Conformational Expansion Underlies the Evolutionary Emergence of Redox Sensitivity in Vertebrate Glucokinases

Conformational Expansion Underlies the Evoluti...

Biochemistry
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librarian
11 views
Chronic elevation of 1.25(OH)2D enhances cholesterol excretion through coordinated regulation of hepatic and intestinal elimination pathways

Chronic elevation of 1.25(OH)2D enhances chole...

Biochemistry
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Chiaki Abe
12 views
Specificity Profiling of the RhoGEF Domain of EhFP10 with EhRho GTPases Involved in Cytoskeleton Remodeling

Specificity Profiling of the RhoGEF Domain of ...

Biochemistry
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Samudrala Gourinath
10 views
Crude Fucus vesiculosus fucoidan demonstrates superior SARS-CoV-2 antiviral activity compared to its pure form: binding kinetics and functional studies

Crude Fucus vesiculosus fucoidan demonstrates ...

Biochemistry
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librarian
10 views
PCanPIE: A group I intron platform for efficient circRNA synthesis at ambient temperatures

PCanPIE: A group I intron platform for efficie...

Biochemistry
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librarian
13 views
The Impact of Dysregulated Lipid Metabolism on the Gut-Brain Axis in Patients with Intracerebral Hemorrhage

The Impact of Dysregulated Lipid Metabolism on...

Biochemistry
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Guoping Wang
9 views
Evaluating β-glucanases as cell wall-permeabilising agents against Phytophthora agathidicida oospores

Evaluating β-glucanases as cell wall-permeabil...

Biochemistry
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librarian
12 views
Evolutionary insights into bilin biosynthesis: Functional characterization of pre-PcyA enzymes

Evolutionary insights into bilin biosynthesis:...

Biochemistry
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librarian
9 views
Hero11 Unlocks TDP-43 Condensate Fluidity via Targeting Inter-Helical Interactions

Hero11 Unlocks TDP-43 Condensate Fluidity via ...

Biochemistry
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librarian
14 views
Redox Regulation in O2-Tolerant Hydrogenases: Insights from two homologues.

Redox Regulation in O2-Tolerant Hydrogenases:...

Biochemistry
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Alexey Silakov
12 views
Molecular characterization of the effector-immunity pair Rhs2-SciX from Salmonella Typhimurium

Molecular characterization of the effector-imm...

Biochemistry
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librarian
10 views
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