Biochemistry

Heterobifunctional Protein Binders Enable Cell Type-Specific Killing Through In-cell Enrichment

Heterobifunctional Protein Binders Enable Cell...

Biochemistry
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librarian
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Collective unstructured interactions drive chromatin binding of transcription factors

Collective unstructured interactions drive chr...

Biochemistry
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librarian
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Comprehensive degron mapping in human transcription factors

Comprehensive degron mapping in human transcri...

Biochemistry
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librarian
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End-product inhibition of the LRRK2-counteracting PPM1H phosphatase

End-product inhibition of the LRRK2-counteract...

Biochemistry
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librarian
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Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site-Specific Post-Translational Modifications of Alpha-Synuclein and Tau

Genetic Code Expansion and Enzymatic Modificat...

Biochemistry
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Elizabeth Rhoades
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Selective Detection of a Key Region in Chemotaxis Signaling Protein Complexes by Solid-State NMR

Selective Detection of a Key Region in Chemota...

Biochemistry
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Lynmarie Thompson
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Structural evidence for metal ion catalysis in the ribosome

Structural evidence for metal ion catalysis in...

Biochemistry
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librarian
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Computational design of dynamic biosensors for emerging synthetic opioids

Computational design of dynamic biosensors for...

Biochemistry
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librarian
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Entry Steps in the Biosynthetic Pathway to DiterpenoidAlkaloids in Delphinium grandiflorum and Aconitum plicatum

Entry Steps in the Biosynthetic Pathway to Dit...

Biochemistry
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librarian
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SyntheMol-RL: a flexible reinforcement learning framework for designing novel and synthesizable antibiotics

SyntheMol-RL: a flexible reinforcement learnin...

Biochemistry
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librarian
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One-Pot Enzymatic ADDing of Click Chemistry Handles for Protein Immobilization and Bioconjugation of Small and Biomolecules

One-Pot Enzymatic ADDing of Click Chemistry Ha...

Biochemistry
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librarian
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Improving proteomic dynamic range with Multiple Accumulation Precursor Mass Spectrometry (MAP-MS)

Improving proteomic dynamic range with Multipl...

Biochemistry
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Brian Searle
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The Critical Role of the C-terminal Lobe of Calmodulin in Activating Eukaryotic Elongation Factor 2 Kinase

The Critical Role of the C-terminal Lobe of Ca...

Biochemistry
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librarian
2 views
Synergistic Action of Commercial Lipase, Lipoxygenases and Proteinase towards PLA Depolymerization

Synergistic Action of Commercial Lipase, Lipox...

Biochemistry
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David Cannella
2 views
Quantification of disease-associated RNA tandem repeats by nanopore sensing

Quantification of disease-associated RNA tande...

Biochemistry
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librarian
3 views
Adaptation of the Chlorella photosynthetic electron transport chain to environmental light conditions

Adaptation of the Chlorella photosynthetic ele...

Biochemistry
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Colin Gates
3 views
Very long chain fatty acids drive 1-deoxy-Sphingolipid toxicity

Very long chain fatty acids drive 1-deoxy-Sphi...

Biochemistry
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librarian
2 views
Inhibition of NF-κB Signaling by the Reactive Glycolytic Metabolite Methylglyoxal

Inhibition of NF-κB Signaling by the Reactive ...

Biochemistry
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librarian
2 views
AI-Guided Discovery of LDHA Inhibitors Targeting Cancer Metabolism Using Machine Learning and Generative Chemistry: An End-to-End Drug Discovery Pipeline

AI-Guided Discovery of LDHA Inhibitors Targeti...

Biochemistry
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librarian
3 views
Specificity profiling of SARS-CoV-2 PLpro using proteome-derived libraries of linear peptides suggests secondary preference for basic motifs

Specificity profiling of SARS-CoV-2 PLpro usin...

Biochemistry
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Oliver Schilling
8 views
Select azo compounds post-translationally modulate HTRA1 abundance and activity potentially through interactions at the trimer interface

Select azo compounds post-translationally modu...

Biochemistry
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librarian
3 views
Monte Carlo track-structure simulation of the impact of Ultra-Hight Dose Rate and oxygen concentration on the Fenton reaction.

Monte Carlo track-structure simulation of the ...

Biochemistry
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librarian
4 views
Chromatin Protection by the Chromosomal Passenger Complex

Chromatin Protection by the Chromosomal Passen...

Biochemistry
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librarian
3 views
Mycobacterial EtfD contains an unusual linear cluster and enables β-oxidation to drive proton pumping by the electron transport chain

Mycobacterial EtfD contains an unusual linear ...

Biochemistry
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Gautier Courbon
4 views
Structures of Fab-stabilized CHIP reveal a conformational switch important in E3 ligase and chaperone functions

Structures of Fab-stabilized CHIP reveal a con...

Biochemistry
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librarian
3 views
Structural Basis of Herpesvirus Helicase-Primase Inhibition by Pritelivir and Amenamevir

Structural Basis of Herpesvirus Helicase-Prima...

Biochemistry
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librarian
4 views
ZNF638 represses the transcription of HBV closed circular DNA involving HUSH complex-mediated histone modifications of epigenetic silencing

ZNF638 represses the transcription of HBV clos...

Biochemistry
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librarian
3 views
Identification and characterization of a small-molecule inhibitor of the Pseudomonas aeruginosa SOS response

Identification and characterization of a small...

Biochemistry
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Laura Cendron
4 views
Alternatively-Spliced CAMKK2 isoforms drive differential metabolic stress response and the regulation of ferroptosis

Alternatively-Spliced CAMKK2 isoforms drive di...

Biochemistry
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Jeongsik Yong
3 views
Antibody targeting the anti-parallel topology of human telomeric G-quadruplex DNA

Antibody targeting the anti-parallel topology ...

Biochemistry
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librarian
3 views
Multiplexed Data-Independent Acquisition (mDIA) to Profile Extracellular Vesicle Proteomes

Multiplexed Data-Independent Acquisition (mDIA...

Biochemistry
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W. Andy Tao
3 views
A close unicellular relative reveals aggregative multicellularity was key to the evolution of animals

A close unicellular relative reveals aggregati...

Biochemistry
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librarian
4 views
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