Biochemistry

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-specific Protease USP18

High-Throughput Synthesis and Screening of a C...

Biochemistry
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Paul Geurink
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Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty-acyltransferase

Cryo-EM structure revealed a novel F-actin bin...

Biochemistry
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Yuxin Mao
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Polymorphic α-Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights from 13C and 1H Solid-State NMR

Polymorphic α-Glucans as Structural Scaffolds ...

Biochemistry
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librarian
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Enhancing the protein fitness of interferon-lambda through computational design and glyco-engineering for prophylactic nasal drugs against respiratory viruses

Enhancing the protein fitness of interferon-la...

Biochemistry
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Hyun Jung Chung
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CRISPR-Cas9 trans-cleavage is hindered by a closed R-loop, an elongated spacer, and an inactive HNH domain

CRISPR-Cas9 trans-cleavage is hindered by a cl...

Biochemistry
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Guillermo Rodrigo
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RNA condensates as platforms for prebiotic chemistry

RNA condensates as platforms for prebiotic che...

Biochemistry
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librarian
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Molecular Matchmakers: How ATP and Small Amphiphilic Molecules Fine-Tune FET Proteins Clusters

Molecular Matchmakers: How ATP and Small Amphi...

Biochemistry
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librarian
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Discovery of a new evolutionarily conserved short linear F-actin binding motif

Discovery of a new evolutionarily conserved sh...

Biochemistry
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Sabine Windhorst
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Engineering a membrane-independent human prothrombinase through parsimonious mutation of factor Xa

Engineering a membrane-independent human proth...

Biochemistry
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librarian
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Structural Heterogeneity of Proteoform-Ligand Complexes in AMP-Activated Protein Kinase Uncovered by Integrated Top-Down Mass Spectrometry

Structural Heterogeneity of Proteoform-Ligand ...

Biochemistry
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librarian
3 views
Single-Molecule Kinetic Exploration of Functional Substates in an Evolving Phosphotriesterase

Single-Molecule Kinetic Exploration of Functio...

Biochemistry
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librarian
4 views
A structural basis for chaperone repression of stress signalling from the endoplasmic reticulum

A structural basis for chaperone repression of...

Biochemistry
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librarian
6 views
Catalytic Mechanism and Differential Alarmone Regulation of a Conserved Stringent Nucleosidase

Catalytic Mechanism and Differential Alarmone ...

Biochemistry
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librarian
4 views
Designed NGF mimetics with reduced nociceptive signatures in neurons

Designed NGF mimetics with reduced nociceptive...

Biochemistry
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librarian
3 views
Preliminary characterization of CbcS from Geobacter sulfurreducens ' Cbc4 complex: a putative novel respiratory pathway

Preliminary characterization of CbcS from Geob...

Biochemistry
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librarian
3 views
Genetic variants linked to neurodevelopmental disorders within the β3-β4 loop of the TRIO PH2 domain release autoinhibition of GEF2 activity.

Genetic variants linked to neurodevelopmental ...

Biochemistry
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Anthony Koleske
3 views
Selectivity profiles and substrate recognition of Rab phosphorylating kinases

Selectivity profiles and substrate recognition...

Biochemistry
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librarian
10 views
Quantification of Wnt3a, Wnt5a and Wnt16 Binding to Multiple Frizzleds Under Physiological Conditions using NanoBit/BRET

Quantification of Wnt3a, Wnt5a and Wnt16 Bindi...

Biochemistry
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librarian
2 views
Acyl-CoA Binding Protein is Dispensable for White and Brown Adipose Tissue Function

Acyl-CoA Binding Protein is Dispensable for Wh...

Biochemistry
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librarian
3 views
Structural and Functional Studies of Rabbit SAMD9 Reveal a Distinct tRNase Module That Underlies the Antiviral Activity

Structural and Functional Studies of Rabbit SA...

Biochemistry
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librarian
3 views
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

A general model for analysis of linear and hyp...

Biochemistry
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Sandro Marana
2 views
Atom level enzyme active site scaffolding using RFdiffusion2

Atom level enzyme active site scaffolding usin...

Biochemistry
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Rohith Krishna
4 views
Gut sulfide metabolism modulates behavior and brain bioenergetics

Gut sulfide metabolism modulates behavior and ...

Biochemistry
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librarian
2 views
Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase

Sperm meet the elevated energy demands to atta...

Biochemistry
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Melanie Balbach
8 views
Energetic and structural control of polyspecificity in a multidrug transporter

Energetic and structural control of polyspecif...

Biochemistry
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librarian
5 views
Long-Distance Trail Running Induces Inflammatory-Associated Protein, Lipid, and Purine Oxidation in Red Blood Cells

Long-Distance Trail Running Induces Inflammato...

Biochemistry
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Travis Nemkov
5 views
Caspase Cleavage of Kaposi Sarcoma-Associated Herpesvirus Proteins: A role for K5 in Preventing Caspase-Mediated Cell Death during Lytic Replication

Caspase Cleavage of Kaposi Sarcoma-Associated ...

Biochemistry
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librarian
6 views
Structural basis of multitasking by the apicoplast DNA polymerase from Plasmodium falciparum

Structural basis of multitasking by the apicop...

Biochemistry
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librarian
5 views
Deltex and RING-UIM E3 ligases cooperate to create a ubiquitin-ADP-ribose hybrid mark on tankyrase, promoting its stabilization

Deltex and RING-UIM E3 ligases cooperate to cr...

Biochemistry
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Susan Smith
8 views
An automated metabolite extraction workflow for global metabolomics analysis using the Agilent Bravo liquid handling platform

An automated metabolite extraction workflow fo...

Biochemistry
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librarian
9 views
Mycolic acid like lipids act as substrates for Mycobacterium tuberculosis melH

Mycolic acid like lipids act as substrates for...

Biochemistry
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librarian
6 views
TUCL-Seq for miRNA single molecule sequencing

TUCL-Seq for miRNA single molecule sequencing

Biochemistry
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librarian
2 views
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