Pharmacology and Toxicology

Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein
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Maarten Dewilde
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Targeted Alpha Therapy with Ac-Macropa-Isatuximab for CD38-positive Hematological Malignancies
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librarian
3 views
Phytoassisted synthesis of biogenic silver nanoparticles using Vernonia amygdalina leaf extract: characterization, antibacterial, anti-inflammatory, and acute toxicity profile
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librarian
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The nitrite reductase activity of xanthine oxidoreductase sustains cardiovascular health
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librarian
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Fatty acid-mediated induction of CYP2E1 activity in HepaRG cells is not systematically associated with exacerbated acetaminophen cytotoxicity
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librarian
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Environmentally Relevant Lead Exposure Impacts Gene Expression in SH-SY5Y Cells Throughout Neuronal Differentiation
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librarian
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Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
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Tangui Maurice
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Discovery and isolation of novel capsaicinoids and their TRPV1-related activity
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librarian
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REDD1 is a determinant of the sensitivity of renal cell carcinoma cells to autophagy inhibition that can be therapeutically exploited by targeting PIM kinase activity
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Steffan Nawrocki
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Comparative antioxidant activity of Ocimum gratissimum and Jatropha tanjorensis 2024.
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librarian
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Transcriptomic analysis reveals lipid metabolism and macrophage involvement associated with nintedanib treatment in a rat bleomycin model
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Martina Bonatti
2 views
Methanol Crude Extract of Litsea Monopetala Leaves combats oxidative stress, clot formation, inflammation and stool frequency in Animal Model
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Zubair Khalid Labu
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Mycotoxin candidalysin impairs epithelial barrier integrity and initiates inflammation in a gut-on-chip model
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Moran Morelli
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In-silico Targeting Phosphodiesterase 5 and In-vivo Evaluation of the Aphrodisiac Effect of Azanza garckeana Fruit
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InnocentMary Ejiofor
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RvD1 and LXA4 inhibitory effects on cardiac voltage-gated potassium channels
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librarian
2 views
Transcriptional phenotype of the anti-parasitic benzodiazepine meclonazepam on the blood fluke Schistosoma mansoni
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librarian
1 view
Chitosan nanocapsules with Alstonia boonei extract modulate the immune system in Wistar rats
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librarian
2 views
Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis	 cholesterol metabolism
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librarian
2 views
Effects of organic and inorganic contaminants and their mixtures on metabolic health and gene expression in developmentally exposed zebrafish
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librarian
1 view
GPCRVS - AI-driven decision support system for GPCR virtual screening
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Dorota Latek
2 views
Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models
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Zbigniew Zaslona
2 views
Dopamine controls the Sensitivity to Manganese induced Dopaminergic neurotoxicity in Caenorhabditis elegans
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Anoopkumar Thekkuveettil
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Cannabidiol Toxicity Driven by Hydroxyquinone Formation
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librarian
4 views
Dose- and time-dependent effects of cobalt protoporphyrin IX on granulocyte mobilization and metabolic markers in mice
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librarian
3 views
Baicalein ameliorates experimental ulcerative colitis recurrency by downregulating neonatal Fc receptor via the NF-κB signaling pathway
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librarian
2 views
Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate Cancer
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librarian
5 views
EFP Analyzer: A fast, accurate, and easy-to-teach program for analyzing Extracellular Field Potentials from iPSC-derived cardiomyocytes
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librarian
5 views
Mitochondrial Dysfunction and ER Stress in CB1 Receptor Antagonist-Induced Apoptosis in Human Neuroblastoma SH-SY5Y Cells
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Kosuke Kataoka
2 views
Hydroxy polyethylene glycol: a solution to evade human pre-existing anti-PEG antibodies for efficient delivery
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Changyou Zhan
2 views
RAPID HIPPOCAMPAL SYNAPTIC POTENTIATION INDUCED BY KETAMINE METABOLITE (2R,6R)-HYDROXYNORKETAMINE PERSISTENTLY PRIMES SYNAPTIC PLASTICITY
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librarian
3 views
A Practical and Safe Model of Nitrogen Mustard Injury in Cornea
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Min Zhao
3 views
Quantification of Signal Amplification for Receptors: The Kd/EC50 Ratio of Full Agonists as a Gain Parameter
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Peter Buchwald
16 views