Pharmacology and Toxicology

DICAR-JP Regulates Ribosome Migration, a New Theory of Mitochondrial Protein Production

DICAR-JP Regulates Ribosome Migration, a New T...

Pharmacology and Toxicology
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librarian
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Animal product-free formation and cultivation of 3D primary hepatocyte spheroids

Animal product-free formation and cultivation ...

Pharmacology and Toxicology
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Maria Karlgren
3 views
Accelerated plastic aging in suspension (APAS): A simple, reproducible approach for the generation of model micro- and nanoplastics through simulated environmental forces

Accelerated plastic aging in suspension (APAS)...

Pharmacology and Toxicology
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librarian
2 views
ArcDFI: Attention Regularization guided by CYP450 Interactions for Predicting Drug-Food Interactions

ArcDFI: Attention Regularization guided by CYP...

Pharmacology and Toxicology
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Donghyeon Park
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Sevoflurane inhibition of the developmentally expressed neuronal sodium channel Nav1.3

Sevoflurane inhibition of the developmentally ...

Pharmacology and Toxicology
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Jiaxin Xiang
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Assessing the potential cardiovascular risk of microdosing the psychedelic LSD in mice

Assessing the potential cardiovascular risk of...

Pharmacology and Toxicology
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librarian
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Andrographolide prevents necroptosis by suppressing generation of reactive oxygen species

Andrographolide prevents necroptosis by suppre...

Pharmacology and Toxicology
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librarian
3 views
A Precision Gene Engineered B Cell Medicine Producing Sustained Levels of Active Factor IX for Hemophilia B Therapy

A Precision Gene Engineered B Cell Medicine Pr...

Pharmacology and Toxicology
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librarian
3 views
treecompareR: Tree Visualizations of Chemical Space

treecompareR: Tree Visualizations of Chemical ...

Pharmacology and Toxicology
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librarian
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TMT-based quantitative proteomic assessment of Vicia sativa induced neurotoxicity by β-cyano-L-alanine and γ-glutamyl-β-cyano-L-alanine in SH-SY5Y cells.

TMT-based quantitative proteomic assessment of...

Pharmacology and Toxicology
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Iain Searle
4 views
A Cheminformatics Workflow for Higher-throughput Modeling of Chemical Exposures from Biosolids

A Cheminformatics Workflow for Higher-throughp...

Pharmacology and Toxicology
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librarian
2 views
Structure-Based Classification of CRISPR/Cas9 Proteins: A Machine Learning Approach to Elucidating Cas9 Allostery

Structure-Based Classification of CRISPR/Cas9 ...

Pharmacology and Toxicology
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librarian
6 views
The non-steroidal mineralocorticoid receptor (MR) antagonist (FINERENONE) reverses Western diet-induced kidney disease by enhancing mitochondrial metabolism and decreasing lipid accumulation and inflammation

The non-steroidal mineralocorticoid receptor (...

Pharmacology and Toxicology
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Moshe Levi
3 views
PAC: A novel translational concordance framework identifies preclinical seizure models with highest predictive validity for clinical focal onset seizures

PAC: A novel translational concordance framewo...

Pharmacology and Toxicology
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Lyndsey Anderson
3 views
Transcriptomic insights into early diagnosis of doxorubicin-induced cardiotoxicity in a rat model

Transcriptomic insights into early diagnosis o...

Pharmacology and Toxicology
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librarian
3 views
Restoration of Susceptibility of blaNDM-bearing Escherichia. coli to Carbapenem Antibiotics by Exogenous N-acetylcysteine

Restoration of Susceptibility of blaNDM-bearin...

Pharmacology and Toxicology
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librarian
3 views
ANALYSIS OF PHYTOEXTRACTS OF MEDICINAL PLANTS FOR ANTIMICROBIAL ACTIVITY AGAINST PATHOGENIC STRAINS OF MICROORGANISMS

ANALYSIS OF PHYTOEXTRACTS OF MEDICINAL PLANTS ...

Pharmacology and Toxicology
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Vasiliy Chokheli
3 views
GM1 and GD3 Gangliosides Attenuate NGF-TrkA and BDNF-TrkB Signaling Dysfunction Associated with Acute Diisopropylfluorophosphate Exposure in Mouse Brain

GM1 and GD3 Gangliosides Attenuate NGF-TrkA an...

Pharmacology and Toxicology
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Alvin Terry
3 views
Primulagenin A is a potent inverse agonist of the nuclear receptor RAR-related orphan receptor gamma (RORγ)

Primulagenin A is a potent inverse agonist of ...

Pharmacology and Toxicology
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Verena Dirsch
8 views
Target engagement studies and kinetic live-cell degradation assays enable the systematic characterization of HDAC6 PROTACs at endogenous protein expression levels

Target engagement studies and kinetic live-cel...

Pharmacology and Toxicology
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librarian
4 views
Field potential Imaging in human iPSC- derived Cardiomyocytes using UHD-CMOS-MEA

Field potential Imaging in human iPSC- derived...

Pharmacology and Toxicology
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librarian
3 views
Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption

Targeting therapeutic nanoparticles to the gli...

Pharmacology and Toxicology
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librarian
4 views
Pregnancy-Dependent Cardioprotection via GPER Activation in Dahl Salt-Sensitive Rats

Pregnancy-Dependent Cardioprotection via GPER ...

Pharmacology and Toxicology
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librarian
4 views
Mapping cellular targets of covalent cancer drugs in the entire mammalian body

Mapping cellular targets of covalent cancer dr...

Pharmacology and Toxicology
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librarian
4 views
A computational workflow for assessing drug effects on temporal signaling dynamics reveals robustness in stimulus-specific NFκB signaling

A computational workflow for assessing drug ef...

Pharmacology and Toxicology
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librarian
5 views
AT1R and Integrin β3 Synergize to Drive Aortic Dissection via Non-Canonical Wnt/β-Catenin Signaling

AT1R and Integrin β3 Synergize to Drive Aortic...

Pharmacology and Toxicology
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librarian
4 views
High doses of electromagnetic radiation pre- and post- fertilization produce different developmental outcomes in Xenopus laevis.

High doses of electromagnetic radiation pre- a...

Pharmacology and Toxicology
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librarian
5 views
Au18(L-NIBC)14 targets ASC oligomerization for autoimmune disease treatment

Au18(L-NIBC)14 targets ASC oligomerization for...

Pharmacology and Toxicology
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librarian
4 views
Interleukin-6 elevates thrombosis via pro-coagulant phospholipids from platelet 12-lipoxygenase in rheumatoid arthritis.

Interleukin-6 elevates thrombosis via pro-coag...

Pharmacology and Toxicology
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librarian
3 views
12/15-Lipoxygenase orchestrates murine wound healing via PPARg-activating oxylipins acting holistically to dampen inflammation.

12/15-Lipoxygenase orchestrates murine wound h...

Pharmacology and Toxicology
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Valerie O'Donnell
5 views
One Tracer, Dual Platforms: Unlocking Versatility of Fluorescent Probes in TR-FRET and NanoBRET Target Engagement Assays

One Tracer, Dual Platforms: Unlocking Versatil...

Pharmacology and Toxicology
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librarian
3 views
Characterization of a novel mouse model of Dopamine Transporter Deficiency Syndrome and pharmacological therapeutic strategies

Characterization of a novel mouse model of Dop...

Pharmacology and Toxicology
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librarian
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