Pharmacology and Toxicology

The dithiocarbamate pesticides maneb and mancozeb disturb the metabolism of lipids and xenobiotics in an in vitro model of metabolic dysfunction-associated steatotic liver disease

The dithiocarbamate pesticides maneb and manco...

Pharmacology and Toxicology
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librarian
4 views
High-throughput screening of more than 30,000 compounds for anthelmintics against gastrointestinal nematode parasites

High-throughput screening of more than 30,000 ...

Pharmacology and Toxicology
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Raffi Aroian
5 views
Molecular Mechanism of Huanglian Jiedu Decoction in Treatment of Alzheimer's Disease based on Network Pharmacology

Molecular Mechanism of Huanglian Jiedu Decocti...

Pharmacology and Toxicology
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librarian
5 views
Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools Monitoring Targeted Protein Degradation

Lysineless HiBiT and NanoLuc Tagging Systems a...

Pharmacology and Toxicology
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Jin Wang
22 views
Effects of alcohol consumption and tobacco smoking on the composition of the ensemble of drug metabolizing enzymes and transporters in human liver

Effects of alcohol consumption and tobacco smo...

Pharmacology and Toxicology
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Bhagwat Prasad
2 views
Gynura procumbens Leaf Extract-Loaded Self-Microemulsifying Drug Delivery System Offers Enhanced Protective Effects in the Hepatorenal Organs of the Experimental Rats

Gynura procumbens Leaf Extract-Loaded Self-Mic...

Pharmacology and Toxicology
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librarian
2 views
Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by reprogramming macrophages and increasing UCP1 expression in vascular smooth muscle cells

Mitochondria-targeted hydrogen sulfide donor r...

Pharmacology and Toxicology
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Aneta Stachowicz
2 views
Crystal structure determination of the antipsychotic drug of olanzapine form III.

Crystal structure determination of the antipsy...

Pharmacology and Toxicology
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librarian
2 views
Oral Exposure to Benzalkonium Chlorides in Male and Female Mice Reveals Sex-Dependent Alteration of the Gut Microbiome and Bile Acid Profile

Oral Exposure to Benzalkonium Chlorides in Mal...

Pharmacology and Toxicology
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librarian
2 views
A selective GSK3β inhibitor, tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL/6J mice

A selective GSK3β inhibitor, tideglusib, decre...

Pharmacology and Toxicology
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Michael Miles
6 views
HYL001, a new potent TGFβ signaling inhibitor that is efficacious against microsatellite stable CRC metastasis in combination with immune checkpoint therapy in mice

HYL001, a new potent TGFβ signaling inhibitor ...

Pharmacology and Toxicology
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librarian
6 views
THE PHYTOPHARMACOLOGICAL EVALUATION OF THE METHANOL ROOT EXTRACT OF AZANZA GARCKEANA (MALVACEAE) ON ISOLATED WISTAR RAT UTERINE SMOOTH MUSCLES.

THE PHYTOPHARMACOLOGICAL EVALUATION OF THE MET...

Pharmacology and Toxicology
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Alfred Chanda
6 views
Design, synthesis and cellular characterization of a new class of IPMK kinase inhibitors

Design, synthesis and cellular characterizatio...

Pharmacology and Toxicology
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Xiaodong Wang
7 views
Experimental parkinsonism induced by tetanus toxin injected into basal ganglia

Experimental parkinsonism induced by tetanus t...

Pharmacology and Toxicology
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Ivica Matak
7 views
Effect Of Ayahuasca on Experimental Models of Ethanol Addiction and Immunohistochemistry Analysis in Rodents

Effect Of Ayahuasca on Experimental Models of ...

Pharmacology and Toxicology
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Victor Distefano Wiltenburg
6 views
Cellulose Rich Food Leads Anxiety through Gut-Brain Axis-mediated Amygdalar Dopamine Upregulation.

Cellulose Rich Food Leads Anxiety through Gut-...

Pharmacology and Toxicology
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Chihiro Nozaki
9 views
5-Deazaflavin (TND1128) and its hybrid analogs are cytoprotective against hydrogen peroxide (H2O2)-induced oxidative stress.

5-Deazaflavin (TND1128) and its hybrid analogs...

Pharmacology and Toxicology
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Kaori Kubota
7 views
Persistent effects of repeated adolescent and adult heroin vapor inhalation in female Wistar rats

Persistent effects of repeated adolescent and ...

Pharmacology and Toxicology
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librarian
6 views
A novel heuristic of rigid docking scores positively correlates with full-length nuclear receptor LRH-1 regulation.

A novel heuristic of rigid docking scores posi...

Pharmacology and Toxicology
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librarian
13 views
Validating the Target Functions and Synergistic Multi-Target, Multi-Pathway Action Mode of Compound Kushen Injection Using CRISPR/CAS

Validating the Target Functions and Synergisti...

Pharmacology and Toxicology
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librarian
7 views
PI3 kinase-unrelated effects of LY294002 and LY303511 on serotonin-induced Ca2+ and cAMP signaling

PI3 kinase-unrelated effects of LY294002 and L...

Pharmacology and Toxicology
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librarian
7 views
Larval motility assay using WMicrotracker: a high throughput test to discriminate between resistance and susceptibility to anthelmintic drugs in nematodes

Larval motility assay using WMicrotracker: a h...

Pharmacology and Toxicology
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Mélanie Alberich
7 views
Mixtures of phthalates disrupt expression of genes related to lipid metabolism and peroxisome proliferator-activated receptor signaling in mouse granulosa cells

Mixtures of phthalates disrupt expression of g...

Pharmacology and Toxicology
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librarian
8 views
Discovery of cyclic peptide natural product inhibitors of Balamuthia mandrillaris

Discovery of cyclic peptide natural product in...

Pharmacology and Toxicology
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librarian
7 views
The effect of Citrus reticulata peel extract containing hesperidin on inhibition of SARS-CoV-2 infection based on pseudovirus entry assays

The effect of Citrus reticulata peel extract c...

Pharmacology and Toxicology
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Endah Puji Septisetyani
7 views
Network pharmacology, single gene survival analysis and molecular docking to study the mechanism of Sotetsuflavone in the treatment of pancreatic cancer

Network pharmacology, single gene survival ana...

Pharmacology and Toxicology
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librarian
5 views
Applying Cell Painting in Non-Tumorigenic Breast Cells to Understand Impacts of Common Chemical Exposures

Applying Cell Painting in Non-Tumorigenic Brea...

Pharmacology and Toxicology
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Justin Colacino
6 views
Dataset of emerging contaminants in surface water, bottom water, porewater, and sediment: Urban and aquaculture impacts in the central and southern coast of Chile

Dataset of emerging contaminants in surface wa...

Pharmacology and Toxicology
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librarian
7 views
Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice

Trazodone, dibenzoylmethane and tauroursodeoxy...

Pharmacology and Toxicology
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librarian
9 views
3-Nitropropionic acid induces histological and behavioral alterations in adult zebrafish: role of antioxidants on behavioral dysfunction

3-Nitropropionic acid induces histological and...

Pharmacology and Toxicology
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Carla Bonan
7 views
Magnesium hydroxide nanoneedles derived from Anthocleista schweinfurthii Gilg (Loganiaceae) support mesenchymal stromal cell proliferation and wound healing

Magnesium hydroxide nanoneedles derived from A...

Pharmacology and Toxicology
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Francois Eya'ane Meva
17 views
Venom-inspired somatostatin receptor 4 (SSTR4) agonists as new drug leads for peripheral pain conditions

Venom-inspired somatostatin receptor 4 (SSTR4)...

Pharmacology and Toxicology
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Walden Bjørn-Yoshimoto
8 views
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