Pharmacology and Toxicology

In vitro genotoxic and mutagenic potentials of combustion particles from marine fuels with different sulfur contents

In vitro genotoxic and mutagenic potentials of...

Pharmacology and Toxicology
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librarian
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Differential Toxicity of Perfluorooctane Sulfonate (PFOS) in Wild-Type and Oatp1d1 Mutant Zebrafish Embryos

Differential Toxicity of Perfluorooctane Sulfo...

Pharmacology and Toxicology
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Tvrtko Smital
2 views
Interspecies interactions alter the antibiotic sensitivity of Pseudomonas aeruginosa

Interspecies interactions alter the antibiotic...

Pharmacology and Toxicology
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librarian
4 views
Striking Long Term Beneficial Effects of Single Dose Psilocybin and Psychedelic Mushroom Extract in the SAPAP3 Rodent Model of OCD-Like Excessive Self-Grooming

Striking Long Term Beneficial Effects of Singl...

Pharmacology and Toxicology
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librarian
11 views
AB-free kava enhances resilience against the adverse health effects of tobacco smoke in mice

AB-free kava enhances resilience against the a...

Pharmacology and Toxicology
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librarian
10 views
Anti-Toxoplasma gondii screening of eight species and bio-guided identification of metabolites of Elaeis guineensis leaves, a preliminary study

Anti-Toxoplasma gondii screening of eight spec...

Pharmacology and Toxicology
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Nangouban Ouattara
13 views
Assessment of Antimicrobial Therapy in Eradicating Chlamydia muridarum in Research Mice: Immune Status and its Impact on Outcomes

Assessment of Antimicrobial Therapy in Eradica...

Pharmacology and Toxicology
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librarian
14 views
Causal, Predictive Or Observational? Different Understandings Of Key Event Relationships For Adverse Outcome Pathways

Causal, Predictive Or Observational? Different...

Pharmacology and Toxicology
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Zheng Zhou
8 views
Comprehensive evaluation of lifespan-extending molecules in C. elegans

Comprehensive evaluation of lifespan-extending...

Pharmacology and Toxicology
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librarian
11 views
Multiple Targets, One Goal: Compounding life-extending effects through Polypharmacology

Multiple Targets, One Goal: Compounding life-e...

Pharmacology and Toxicology
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Peter Check
9 views
Long-term NMN treatment increases lifespan and healthspan in mice in a sex dependent manner

Long-term NMN treatment increases lifespan and...

Pharmacology and Toxicology
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David Sinclair
14 views
Preliminary pharmacokinetics and in vivo studies indicate analgesic and stress mitigation effects of a novel NMDA receptor modulator

Preliminary pharmacokinetics and in vivo studi...

Pharmacology and Toxicology
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Blaise Costa
28 views
Preliminary pharmacokinetics and in vivo studies indicate analgesic and stress mitigation effects of a novel NMDA receptor modulator

Preliminary pharmacokinetics and in vivo studi...

Pharmacology and Toxicology
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Blaise Costa
29 views
Scientific note on the potential beneficial effect of 1-octen-3-ol on the survival of Apis mellifera chronically exposed to low doses of fipronil.

Scientific note on the potential beneficial ef...

Pharmacology and Toxicology
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Philippe Bouchard
15 views
Assessing mechanisms driving phenol isopropylated phosphate (IPP)- induced larval photomotor response deficits in zebrafish

Assessing mechanisms driving phenol isopropyla...

Pharmacology and Toxicology
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librarian
8 views
Toxicogenomic Assessment of In Vitro Macrophages Exposed to Profibrotic Challenge.

Toxicogenomic Assessment of In Vitro Macrophag...

Pharmacology and Toxicology
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librarian
13 views
Drugs targeting microRNAs that regulate DNA damage sensing and repair mechanisms: A computational drug discovery approach

Drugs targeting microRNAs that regulate DNA da...

Pharmacology and Toxicology
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S Bilachi
42 views
Advanced Cardiovascular Toxicity Screening: Integrating Human iPSC-Derived Cardiomyocytes with In Silico Models

Advanced Cardiovascular Toxicity Screening: In...

Pharmacology and Toxicology
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librarian
8 views
Unveiling the mechanisms of black phosphorus nanosheets-induced viable but non-culturable state in Bacillus tropicus

Unveiling the mechanisms of black phosphorus n...

Pharmacology and Toxicology
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librarian
12 views
Data-Driven Discovery of Feedback Mechanisms in Acute Myeloid Leukaemia: Alternatives to classical models using Deep Nonlinear Mixed Effect modeling and Symbolic Regression

Data-Driven Discovery of Feedback Mechanisms i...

Pharmacology and Toxicology
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Carl Julius Martensen
17 views
Activation of NLRP3 inflammasome/pyroptosis by protease inhibitor atazanavir at high concentrations is mediated through mitochondrial dysfunction

Activation of NLRP3 inflammasome/pyroptosis by...

Pharmacology and Toxicology
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Elijah Paintsil
20 views
Transcutaneous delivery of disease specific PI3K/Akt/mTOR inhibitor based hybrid nanoparticles in hydrogel system for the management of psoriasis: Insights from in vivo studies

Transcutaneous delivery of disease specific PI...

Pharmacology and Toxicology
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librarian
12 views
Phthalate monoesters affect membrane fluidity and cell-cell contacts in endometrial stromal cell lines

Phthalate monoesters affect membrane fluidity ...

Pharmacology and Toxicology
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librarian
12 views
Synthesis and pharmacological characterization of UVI3502, a novel cannabinoid receptor 1 (CB1) antagonist/inverse agonist

Synthesis and pharmacological characterization...

Pharmacology and Toxicology
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Rafael Rodríguez-Puertas
13 views
Increased 5-HT2A receptor signalling efficacy differentiates serotonergic psychedelics from non-psychedelics

Increased 5-HT2A receptor signalling efficacy ...

Pharmacology and Toxicology
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Aurelija Ippolito
22 views
Xenometabolome of Early-Life Stage Salmonids Exposed to 6PPD-Quinone

Xenometabolome of Early-Life Stage Salmonids E...

Pharmacology and Toxicology
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librarian
10 views
Historical texts as a potential resource for plant-derived natural products against SARS-CoV-2 - the example of the Receptarium of Burkhard III von Hallwyl from 16th century Switzerland

Historical texts as a potential resource for p...

Pharmacology and Toxicology
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Nina Vahekeni
28 views
Nitazoxanide ameliorates OVA-induced airway inflammation in asthmatic mice via p38-MAPK/ NFκB and AMPK/STAT3 pathways

Nitazoxanide ameliorates OVA-induced airway in...

Pharmacology and Toxicology
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librarian
25 views
Development of a Time-Resolved Fluorescence Resonance Energy Transfer ultra-high throughput screening assay for targeting SYK and FCER1G interaction

Development of a Time-Resolved Fluorescence Re...

Pharmacology and Toxicology
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Yuhong Dua
18 views
Identification of non-charged 7.44 analogs interacting with the NHR2 domain of RUNX1-ETO and exhibiting an improved, selective antiproliferative effect in RUNX-ETO positive cells

Identification of non-charged 7.44 analogs int...

Pharmacology and Toxicology
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librarian
16 views
Exploring Kp,uu,BBB Values Smaller than Unity in Remoxipride: A Physiologically-Based CNS Model Approach Highlighting Brain Metabolism in Drugs with Passive Blood-Brain Barrier Transport

Exploring Kp,uu,BBB Values Smaller than Unity ...

Pharmacology and Toxicology
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Elizabeth de Lange
13 views
A Mechanistic Approach to Optimize Combination Antibiotic Therapy

A Mechanistic Approach to Optimize Combination...

Pharmacology and Toxicology
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Peter Abel zur Wiesch
15 views
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