Systems Biology

Morphomechanically-Informed Spatial Curvature Sequencing in Prostate Cancer

Morphomechanically-Informed Spatial Curvature ...

Systems Biology
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librarian
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Regulatory Bias Constrains Epigenetic Aging Trajectories

Regulatory Bias Constrains Epigenetic Aging Tr...

Systems Biology
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Taisiia Morozova
1 view
Flux-species sampling enables holistic exploration of biocircuit behavior

Flux-species sampling enables holistic explora...

Systems Biology
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librarian
4 views
Rod pathway blockade improves visual function in a mouse model of photoreceptor degeneration

Rod pathway blockade improves visual function ...

Systems Biology
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Teresa Puthussery
3 views
Quantitative Description of C. elegans mRNA Landscapes From High Coverage Single Cell Transcriptomes

Quantitative Description of C. elegans mRNA La...

Systems Biology
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Denis Dupuy
5 views
ChatGEM: An Agentic Architecture Enabling Interactive Simulation of Genome-Scale Metabolic Models

ChatGEM: An Agentic Architecture Enabling Inte...

Systems Biology
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librarian
4 views
Dynamic knowledge representation of blood brain barrier activation, injury and restitution with a novel agent-based model

Dynamic knowledge representation of blood brai...

Systems Biology
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librarian
4 views
A hybrid machine learning and enzyme-constrained metabolic model for ab initio prediction of proteome reallocation

A hybrid machine learning and enzyme-constrain...

Systems Biology
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librarian
2 views
Diversity and evolution of the transcriptional regulatory networks of Pseudomonas strains revealed using machine learning

Diversity and evolution of the transcriptional...

Systems Biology
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librarian
2 views
Experimentally calibrated computational modeling of inflammation and vascular remodeling in breast cavity healing following breast-conserving surgery

Experimentally calibrated computational modeli...

Systems Biology
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librarian
7 views
Textural features for pathway-level representation of omics data in biological networks

Textural features for pathway-level representa...

Systems Biology
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librarian
13 views
Deep Visual Proteomics links vascular smooth muscle cell phenotypes to atherosclerotic plaque stability

Deep Visual Proteomics links vascular smooth m...

Systems Biology
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librarian
10 views
Coupled Cell-Intrinsic and Microenvironmental Heterogeneity Drives Divergent Trajectories in Castration-Resistant Prostate Cancer

Coupled Cell-Intrinsic and Microenvironmental ...

Systems Biology
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librarian
11 views
Predicting the protein interaction landscape of a mycobacterial pathogen

Predicting the protein interaction landscape o...

Systems Biology
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librarian
10 views
Large-scale, interpretable gene regulatory network inference through biologically informed matrix factorization

Large-scale, interpretable gene regulatory net...

Systems Biology
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librarian
10 views
Beta-adrenergic receptor activation during stress reduces the abundance of commensal Clostridia in the mouse gut

Beta-adrenergic receptor activation during str...

Systems Biology
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Brian Corbett
16 views
Axolotl regeneration reveals a dormant cis-regulatory grammar conserved across vertebrate genomes

Axolotl regeneration reveals a dormant cis-reg...

Systems Biology
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librarian
13 views
Gene Regulatory Networks that support Multi-Fate Cellular Decisions

Gene Regulatory Networks that support Multi-Fa...

Systems Biology
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librarian
15 views
Diversity in transcriptomics without cell types

Diversity in transcriptomics without cell types

Systems Biology
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Leyi Jiang
15 views
A Spatial Agent-Based Model of AGE-RAGE Feedback in Hepatic Fibrosis Reveals Stage-Dependent Irreversibility Thresholds

A Spatial Agent-Based Model of AGE-RAGE Feedba...

Systems Biology
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librarian
24 views
Large-scale analysis of optimisation methods for parameter estimation problems in the life sciences

Large-scale analysis of optimisation methods f...

Systems Biology
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librarian
16 views
A Bioengineered Live Biotherapeutic Exploits Inflammation to Restore Gut Liver Brain Axis Function under Diet-Induced Stress

A Bioengineered Live Biotherapeutic Exploits I...

Systems Biology
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Sanjoy Ghosh
12 views
Regulatory memory and growth-coupled inheritance shape nutrient-dependent flagella number variation in Salmonella

Regulatory memory and growth-coupled inheritan...

Systems Biology
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librarian
12 views
Metabolomic signatures support the diagnostics of peritoneal endometriosis using generalised linear models

Metabolomic signatures support the diagnostics...

Systems Biology
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Tea Lanišnik Rižner
13 views
HetNetEX: Exact Asymptotic Inference in Heterogeneous Biomedical Knowledge Graphs

HetNetEX: Exact Asymptotic Inference in Hetero...

Systems Biology
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librarian
12 views
How p53 stress memory could redirect JAK/STAT1 antiviral signalling: a model-based prediction.

How p53 stress memory could redirect JAK/STAT1...

Systems Biology
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librarian
17 views
Nutritional Anthelmintics: Chicory Reconfigures the Equine Holobiont Across Microbial, Parasitic, and Host Scales

Nutritional Anthelmintics: Chicory Reconfigure...

Systems Biology
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Núria Mach
14 views
Synthesizing Mechanistic Hypotheses from Single-Cell Omics via Discretized Feature Attribution and Empirical Language Model Grounding

Synthesizing Mechanistic Hypotheses from Singl...

Systems Biology
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Neil Lin
19 views
Kinome-wide CRISPR/Cas9-knockout screening reveals critical protein kinases in vasopressin V2-receptor signaling

Kinome-wide CRISPR/Cas9-knockout screening rev...

Systems Biology
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librarian
20 views
Monocyte-amplified transcriptional signatures of human diseases

Monocyte-amplified transcriptional signatures ...

Systems Biology
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librarian
14 views
Quantifying the Information Capacity of DNA Methylation as an Epigenetic Memory System

Quantifying the Information Capacity of DNA Me...

Systems Biology
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Ildefonso Mtz. De la Fuente
14 views
Declines in mRNA synthesis set the rate of organismal aging

Declines in mRNA synthesis set the rate of org...

Systems Biology
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librarian
14 views
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