Systems Biology

Spatially resolved transcriptomic and proteomic profiling reveals cell interaction programs that predict Barrett's esophagus progression

Spatially resolved transcriptomic and proteomi...

Systems Biology
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librarian
1 view
Susagi: A Microbiome World Model

Susagi: A Microbiome World Model

Systems Biology
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librarian
2 views
Homeostatic feedback model of energy metabolism with adaptive enzyme levels exhibits problem solving behavior

Homeostatic feedback model of energy metabolis...

Systems Biology
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Michael Levin
2 views
Talk2QSP: Deriving Executable Scenarios from Unstructured Literature via Human-in-the-Loop Agents

Talk2QSP: Deriving Executable Scenarios from U...

Systems Biology
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librarian
0 views
Learning activator-inhibitor dynamics at the cell cortex with neural likelihood ratio estimation

Learning activator-inhibitor dynamics at the c...

Systems Biology
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Ondrej Maxian
3 views
Systemic stress states are reversed by NPBWR1 inhibition

Systemic stress states are reversed by NPBWR1 ...

Systems Biology
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librarian
7 views
Unraveling the metabolic interactions of a Dehalobacter-containinganaerobic mixed culture for bioremediation

Unraveling the metabolic interactions of a Deh...

Systems Biology
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librarian
8 views
Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures

Scalable longitudinal imaging and transcriptom...

Systems Biology
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Mostafa Ronaghi
13 views
Mathematical Modeling of the Canonical Aryl Hydrocarbon Receptor Pathway

Mathematical Modeling of the Canonical Aryl Hy...

Systems Biology
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librarian
12 views
Ensemble kinetic modelling links residual enzyme activity to clinical symptoms in mitochondrial β-oxidation defects

Ensemble kinetic modelling links residual enzy...

Systems Biology
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librarian
13 views
A unified framework links infant vulnerability with aging-related mortality dynamics

A unified framework links infant vulnerability...

Systems Biology
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librarian
13 views
COCOA.jl: A Julia package for high-performance analysis of concordance and kinetic modules in biochemical networks

COCOA.jl: A Julia package for high-performance...

Systems Biology
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librarian
14 views
Robotic perturbation proteomics and AI agents enable scalable drug mechanism discovery

Robotic perturbation proteomics and AI agents ...

Systems Biology
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Yuming Jiang
29 views
Multi-omic analysis identifies mitochondrial dysfunction as a conserved driver of acute severity and long-term complications in RSV infection

Multi-omic analysis identifies mitochondrial d...

Systems Biology
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librarian
13 views
Bion-M 2 Biosatellite: Multisystem Mouse Responses to 30 Days in High-Latitude Orbit as a Deep-Space Analog

Bion-M 2 Biosatellite: Multisystem Mouse Respo...

Systems Biology
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librarian
17 views
Box-Counting Fractal Dimensions of Cranial Suture: Effects of Measurement Conditions and Model-Based Reproduction of Fractal-Like Patterns

Box-Counting Fractal Dimensions of Cranial Sut...

Systems Biology
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Takashi Miura
18 views
Lineage-specific lncRNAs critically determine cross-species differences in tumors

Lineage-specific lncRNAs critically determine ...

Systems Biology
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librarian
19 views
REDUCED-PRECISION STOCHASTIC SIMULATION FOR MATHEMATICAL BIOLOGY

REDUCED-PRECISION STOCHASTIC SIMULATION FOR MA...

Systems Biology
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librarian
21 views
Network topology dictates sequential drug efficacy through bistability-mediated state switching

Network topology dictates sequential drug effi...

Systems Biology
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librarian
17 views
The Limits of Cross-Species WGCNA: Library Imbalance and Signal Dilution Constrain Effector Gene Recovery in Dual-Organism RNA-seq

The Limits of Cross-Species WGCNA: Library Imb...

Systems Biology
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librarian
19 views
Systems modeling identifies phenotype-determining signaling pathways controlled by phosphatase PTPRJ in diverse receptor tyrosine kinase activation settings

Systems modeling identifies phenotype-determin...

Systems Biology
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librarian
21 views
A Scalable Sign-Aware Multi-Omics Knowledge Graph Foundation Model for Mechanistic Drug Action and Clinical Response Predictions

A Scalable Sign-Aware Multi-Omics Knowledge Gr...

Systems Biology
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Lei Xie
21 views
A Comprehensive Mathematical Model of Avidity in Cytokine Signaling

A Comprehensive Mathematical Model of Avidity ...

Systems Biology
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librarian
19 views
A low-dimensional transcriptional code enables decoding of BMP/TGFβ signaling from single-cell transcriptomes

A low-dimensional transcriptional code enables...

Systems Biology
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librarian
30 views
A transcriptional patient map of systemic lupus erythematosus reveals disease-related multicellular immune programs conserved between blood and kidney

A transcriptional patient map of systemic lupu...

Systems Biology
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librarian
31 views
A unified framework for causal gene regulatory network inference grounded in orthogonal molecular evidence

A unified framework for causal gene regulatory...

Systems Biology
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B. Franklin Pugh
28 views
Bidirectional network hubs: NT-genes as optimal targets for partial cancer reversal

Bidirectional network hubs: NT-genes as optima...

Systems Biology
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Augusto Gonzalez
30 views
DrugPTM-Bench: A Large-Scale Dataset for Predictive Modeling of Drug-Induced Cell Type-Specific Protein Post-Translational Modifications

DrugPTM-Bench: A Large-Scale Dataset for Predi...

Systems Biology
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Amitesh Badkul
34 views
Aging Rhesus Macaque show tissue and sex-specific balance of drifting and coordinated miRNA programs

Aging Rhesus Macaque show tissue and sex-speci...

Systems Biology
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librarian
33 views
A Minimal Regulatory Spatial Model for Emergent Multicellular Organization in Dissipative Environments

A Minimal Regulatory Spatial Model for Emergen...

Systems Biology
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librarian
29 views
Proteome-aware organ proxy aging clocks

Proteome-aware organ proxy aging clocks

Systems Biology
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librarian
44 views
Data-driven lifespan transitions: cortical morphometry and intrinsic differences across network scales

Data-driven lifespan transitions: cortical mor...

Systems Biology
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Rose Cuthbertson
35 views
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