Systems Biology

The phosphatases TCPTP, PTPN22, and SHP1 play unique roles in T cell phosphotyrosine maintenance and feedback regulation of the TCR

The phosphatases TCPTP, PTPN22, and SHP1 play ...

Systems Biology
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librarian
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Machine Learning Meets Pharmacokinetics: A Comparative Analysis of Predictive Models for Plasma Concentration-Time Profiles

Machine Learning Meets Pharmacokinetics: A Com...

Systems Biology
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librarian
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An integrative framework linking molecular signatures and locomotory phenotypes in space-induced sarcopenia

An integrative framework linking molecular sig...

Systems Biology
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Brendan Ball
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A multilayer network approach elucidates time- and tissue-specific developmental and aging processes

A multilayer network approach elucidates time-...

Systems Biology
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Jörg Menche
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miRNA-mRNA network analysis identifies PAX5 as a potential regulator of adaptive immune response in COPD

miRNA-mRNA network analysis identifies PAX5 as...

Systems Biology
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librarian
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Unraveling Cross-Cellular Communication in Cannabis sativa Sex Determination: A Network Ontology Transcript Annotation (Nota) Analysis.

Unraveling Cross-Cellular Communication in Can...

Systems Biology
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Leonardo Orozco
6 views
Context-dependent spatial multicellular network motifs for single-cell spatial biology

Context-dependent spatial multicellular networ...

Systems Biology
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librarian
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Identification and Overexpression of Endogenous Transcription Factors to Enhance Lipid Accumulation in the Commercially Relevant Species Chlamydomonas pacifica

Identification and Overexpression of Endogenou...

Systems Biology
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Stephen Mayfield
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EMMAi: fast enzyme-allocation constraints in GEMs for improved biomass prediction across carbon sources

EMMAi: fast enzyme-allocation constraints in G...

Systems Biology
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librarian
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The zoo of the gene networks capable of pattern formation by extracellular signaling

The zoo of the gene networks capable of patter...

Systems Biology
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librarian
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Baseline State for Pulmonary Vasculature with Pulmonary Arterial Hypertension: Effect of Geometric Remodeling and Metabolic Shift

Baseline State for Pulmonary Vasculature with ...

Systems Biology
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librarian
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Multiomic clocks to predict phenotypic age in mice

Multiomic clocks to predict phenotypic age in mice

Systems Biology
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librarian
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MONTAGE: A Computation Framework to Identify Spatially Resolved Functional Enrichment Gradients in the Tissue Microenvironment via Spatial Communities

MONTAGE: A Computation Framework to Identify S...

Systems Biology
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Sylvia Plevritis
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Single-mRNA imaging and modeling reveal coupled translation initiation and elongation rates

Single-mRNA imaging and modeling reveal couple...

Systems Biology
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librarian
2 views
Quantifying cancer- and drug-induced changes in Shannon information capacity of RTK signaling

Quantifying cancer- and drug-induced changes i...

Systems Biology
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librarian
0 views
PEtab.jl: Advancing the Efficiency and Utility of Dynamic Modelling

PEtab.jl: Advancing the Efficiency and Utility...

Systems Biology
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librarian
4 views
Minimal Gene Signatures Enable High-Accuracy Prediction of Antibiotic Resistance in Pseudomonas aeruginosa

Minimal Gene Signatures Enable High-Accuracy P...

Systems Biology
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librarian
3 views
Recurrent Emergence of Boundary Cell Types During Evolution of Floral Bullseye Patterns

Recurrent Emergence of Boundary Cell Types Dur...

Systems Biology
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Steven Oud
5 views
JNK activation dynamics drive distinct gene expression patterns over time mediated by mRNA stability

JNK activation dynamics drive distinct gene ex...

Systems Biology
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librarian
3 views
Regulatory logic of human cortex evolution by combinatorial perturbations

Regulatory logic of human cortex evolution by ...

Systems Biology
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Michael Boettcher
3 views
Response metrics of T-cell activation models

Response metrics of T-cell activation models

Systems Biology
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librarian
4 views
Perturbational fitness analysis of CRISPR screens uncovers information-theoretic relation between gene function and selection

Perturbational fitness analysis of CRISPR scre...

Systems Biology
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librarian
4 views
Power-law memory governs bacterial adaptation and learning in fluctuating environments

Power-law memory governs bacterial adaptation ...

Systems Biology
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Josiah Kratz
3 views
A Cross-Species Generative Cell Atlas Across 1.5 Billion Years ofEvolution: The TranscriptFormer Single-cell Model

A Cross-Species Generative Cell Atlas Across 1...

Systems Biology
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librarian
22 views
Inside-Out: Modeling the link between Zika virus viral dynamics within hosts and transmission to vectors across host species and virus strains

Inside-Out: Modeling the link between Zika vir...

Systems Biology
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librarian
4 views
Mass spectrometry-based quantification of proteins and post-translational modifications in dried blood: longitudinal sampling of patients with sepsis in Tanzania

Mass spectrometry-based quantification of prot...

Systems Biology
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Matthew Foster
4 views
Heterogeneous therapy-resistant cancer cells have distinct and exploitable drug sensitivity profiles

Heterogeneous therapy-resistant cancer cells h...

Systems Biology
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librarian
19 views
A modelling assessment for the impact of control measures on highly pathogenic avian influenza transmission in poultry in Great Britain

A modelling assessment for the impact of contr...

Systems Biology
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Christopher Davis
11 views
Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype-specific, and severity-linked alterations

Plasma lipidome dysregulation in frontotempora...

Systems Biology
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librarian
7 views
Ubiquitous systems drift in the evolution of development

Ubiquitous systems drift in the evolution of d...

Systems Biology
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librarian
9 views
Time-series RNA-Seq and data-driven network inference unveil dynamics of cell activation, survival and crosstalk in Chronic Lymphocytic Leukaemia in vitro models

Time-series RNA-Seq and data-driven network in...

Systems Biology
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Vera Pancaldi
8 views
Parameter Estimation and Model Selection for the Quantitative Analysis of Oncolytic Virus Therapy in Zebrafish

Parameter Estimation and Model Selection for t...

Systems Biology
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Yuhong Liu
8 views
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