Bioinformatics

Integrating Histology with Spatial Molecular Programs Using a Multimodal Foundation Model

Integrating Histology with Spatial Molecular P...

Bioinformatics
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Zongxu Zhang
24 views
Integrating Histology with Spatial Molecular Programs Using a Multimodal Foundation Model

Integrating Histology with Spatial Molecular P...

Bioinformatics
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Zongxu Zhang
28 views
Distinct fibrotic, epithelial and immune transcriptomic programs in phenotypes of chronic lung allograft dysfunction

Distinct fibrotic, epithelial and immune trans...

Bioinformatics
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craig-thorburn
42 views
CANCAN: high-resolution copy number and mutation heterogeneity analysis of DNA sequence data for clinical applications

CANCAN: high-resolution copy number and mutati...

Bioinformatics
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librarian
66 views
ToxCastLite: A portable semantic evidence graph linking in vitro bioactivity, in vivo toxicity, and exposure-use context

ToxCastLite: A portable semantic evidence grap...

Bioinformatics
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librarian
81 views
PocketBagger: Generalizable pocket druggability prediction via positive-unlabeled learning

PocketBagger: Generalizable pocket druggabilit...

Bioinformatics
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librarian
67 views
Multi-Scale Tri-Modal Histology Dataset Integrating Tumor Morphology, Immune Patterns, and Clinical Outcomes

Multi-Scale Tri-Modal Histology Dataset Integr...

Bioinformatics
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librarian
86 views
HESTIA: Scalable Multimodal Integration of Histology and High-Resolution Spatial Transcriptomics for Robust Spatial Domain Identification

HESTIA: Scalable Multimodal Integration of His...

Bioinformatics
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librarian
54 views
Interpretable Predictive Modeling for Medical Data Using Boolean Rule-aware Regression

Interpretable Predictive Modeling for Medical ...

Bioinformatics
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librarian
68 views
Elab2ARC: A Browser-Based Workspace for Converting Free-Text Protocols into rich FAIR digital objects

Elab2ARC: A Browser-Based Workspace for Conver...

Bioinformatics
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Sabrina Zander
83 views
A unified benchmark of synthetic data generation for clinical transcriptomic cancer cohorts

A unified benchmark of synthetic data generati...

Bioinformatics
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Christophe BATTAIL
76 views
Identifying Treatment Related Signatures In Glioblastoma Using KaleidoCell

Identifying Treatment Related Signatures In Gl...

Bioinformatics
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Jean Radig
76 views
Biological foundation models illuminate annotation blind spots in evolutionarily divergent genomes

Biological foundation models illuminate annota...

Bioinformatics
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librarian
74 views
TransXplorer: An automated translational discovery platform for RNA-seq data

TransXplorer: An automated translational disco...

Bioinformatics
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Varinder Madhav Verma
83 views
The human gut virome is a non-redundant and clinically informative component of the microbiome

The human gut virome is a non-redundant and cl...

Bioinformatics
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librarian
63 views
A modular Bayesian framework for inferring transmission networks from polyclonal infections, with application to Plasmodium falciparum

A modular Bayesian framework for inferring tra...

Bioinformatics
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librarian
73 views
Pan-Viral Conformational Landscapes of Frameshifting Elements Reveal Length-Dependent Plasticity and Antisense-Driven Structural Reprogramming

Pan-Viral Conformational Landscapes of Framesh...

Bioinformatics
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librarian
69 views
Deep learning models for chemical perturbation prediction do not yet utilise drug molecular features

Deep learning models for chemical perturbation...

Bioinformatics
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librarian
76 views
Metabolic Self-Organization: Emergence of Autonomous Agency in a Metabolically Constrained LLMs

Metabolic Self-Organization: Emergence of Auto...

Bioinformatics
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librarian
68 views
Physics-Informed Neural Networks for Parameter Recovery in the Repressilator Oscillatory Model

Physics-Informed Neural Networks for Parameter...

Bioinformatics
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Jordi Villà-Freixa
77 views
Exploring the Mechanism of Na⁺/K⁺-ATPase (NKA) and 20-HETE Ligand Interactions by in-silico modeling

Exploring the Mechanism of Na⁺/K⁺-ATPase (NKA)...

Bioinformatics
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librarian
64 views
TDP-43 regulates chromatin looping and gene transcription through binding and stabilizing DNA G-quadruplex structures

TDP-43 regulates chromatin looping and gene tr...

Bioinformatics
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librarian
64 views
Machine learning-based Personalized Dietary Recommendations to Achieve Desired Gut Microbial Compositions

Machine learning-based Personalized Dietary Re...

Bioinformatics
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librarian
69 views
Improving Variant Effect Prediction by Steering Sparse Mechanistic Features in Protein Language Models

Improving Variant Effect Prediction by Steerin...

Bioinformatics
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Yonghong He
62 views
DeSpotX: Identifiability-Based Decontamination for Spatial Transcriptomics

DeSpotX: Identifiability-Based Decontamination...

Bioinformatics
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librarian
70 views
Integrating trajectory inference and gene regulatory network analysis to resolve transcriptional programs of T cell state transitions in the tumor microenvironment

Integrating trajectory inference and gene regu...

Bioinformatics
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librarian
64 views
LOCALE: Local-Alignment Embeddings for Noise-Robust DNA Search at SRA Scale

LOCALE: Local-Alignment Embeddings for Noise-R...

Bioinformatics
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librarian
60 views
Evaluation of MeaSeq: comprehensive analysis and reporting of measles virus whole genome sequences.

Evaluation of MeaSeq: comprehensive analysis a...

Bioinformatics
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librarian
60 views
A multi-omic, spatial, and whole-slide image dataset of lung neuroendocrine tumours from the lungNENomics cohort

A multi-omic, spatial, and whole-slide image d...

Bioinformatics
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Nicolas Alcala
55 views
BRIDGE-GRN: Role-Aware Bi-Tower Graph Learning with Cross-View Contrast for Directed Gene Regulatory Network Inference

BRIDGE-GRN: Role-Aware Bi-Tower Graph Learning...

Bioinformatics
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librarian
63 views
Structure tokens sharpen the feature vocabulary of protein language models

Structure tokens sharpen the feature vocabular...

Bioinformatics
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librarian
62 views
Benchmarking Boltz-2 for Screening of Therapeutic Antibody-Antigen Interactions

Benchmarking Boltz-2 for Screening of Therapeu...

Bioinformatics
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Alexandra Fieux-Castagnet
68 views
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