Bioinformatics

TrioNsight: Building a meta-predictor to evaluate the clinical impact of TrioN-like Dbl-homology domain variants

TrioNsight: Building a meta-predictor to evalu...

Bioinformatics
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Alperen Taciroğlu
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IOBRpy enables agentic multi-omics decoding of anti-tumor immunity

IOBRpy enables agentic multi-omics decoding of...

Bioinformatics
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librarian
1 view
AI4Life Open Calls and Public Challenges: why, how, and what we have learned.

AI4Life Open Calls and Public Challenges: why,...

Bioinformatics
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librarian
1 view
Integrative structure determination of a human mitochondrial contact site and cristae organizing system (MICOS) sub-assembly

Integrative structure determination of a human...

Bioinformatics
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librarian
2 views
De Novo Design of Protein Switches with Diffusion-Based Ensemble Sampling

De Novo Design of Protein Switches with Diffus...

Bioinformatics
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librarian
2 views
The topology of transmembrane protein-protein interaction interfaces is encoded in their physicochemical features

The topology of transmembrane protein-protein ...

Bioinformatics
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Evandro Ferrada
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CSOA: A Novel Single-Cell Gene Set Enrichment Analysis Method with Comprehensive Benchmarking

CSOA: A Novel Single-Cell Gene Set Enrichment ...

Bioinformatics
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Xueli Xu
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Evolutionary divergence of LRRK2 interaction domains contributes to human- and mouse-specific protein interaction networks

Evolutionary divergence of LRRK2 interaction d...

Bioinformatics
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librarian
2 views
Binary node clustering via contrastive learning for haplotype phasing in de novo genome assembly

Binary node clustering via contrastive learnin...

Bioinformatics
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librarian
2 views
seqsizzle: decoding complex barcode and adapter architectures in long-read sequencing data

seqsizzle: decoding complex barcode and adapte...

Bioinformatics
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Changqing Wang
6 views
SPgen: Proteome-wide Spatial Proteomics generation using multi-modality foundation models

SPgen: Proteome-wide Spatial Proteomics genera...

Bioinformatics
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librarian
2 views
Representative vs. Load-bearing Layers: A Dissociation in Genomic Foundation Models

Representative vs. Load-bearing Layers: A Diss...

Bioinformatics
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librarian
2 views
OmicsLake: Versioned, Agent-Aware Data Lineage for R/Bioconductor Workflows

OmicsLake: Versioned, Agent-Aware Data Lineage...

Bioinformatics
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librarian
2 views
Stratified Immune Profiling Uncovers Prognostic Heterogeneity Beyond MYCN Amplification and Age in Neuroblastoma

Stratified Immune Profiling Uncovers Prognosti...

Bioinformatics
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librarian
2 views
An automated platform for spatial functional modeling and fingerprint analysis of tissue molecular landscapes

An automated platform for spatial functional m...

Bioinformatics
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Saumyadipta Pyne
2 views
PepCL: A replay-based continual learning framework for updating peptide-MHC models

PepCL: A replay-based continual learning frame...

Bioinformatics
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Prathamesh Chati
2 views
A new set of DNA methylation variants in the human genome show predominant tissue specificity and sensitivity to reprogramming with a potential for disease susceptibility.

A new set of DNA methylation variants in the h...

Bioinformatics
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librarian
6 views
ProtSyntax: a protein large language model for decoding post-translational modification syntax and function

ProtSyntax: a protein large language model for...

Bioinformatics
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librarian
4 views
GCM: metric-guided clustering by genetic algorithm for correlation-defined modules

GCM: metric-guided clustering by genetic algor...

Bioinformatics
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Luis Javier Madrigal-Roca
5 views
scRepresenter: a workflow for computing, integrating and benchmarking cellular representations in single-cell transcriptomics

scRepresenter: a workflow for computing, integ...

Bioinformatics
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Andre Lamurias
6 views
Age Stratified Meta Transcriptomic Analysis Reveals Early and Core Dysregulated Pathways in Parkinson's Disease

Age Stratified Meta Transcriptomic Analysis Re...

Bioinformatics
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Dimple Davray
5 views
BaiZe: A Multi-View Dynamic Framework for Simulating and Interpreting Cellular Responses Across Perturbation Contexts

BaiZe: A Multi-View Dynamic Framework for Simu...

Bioinformatics
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librarian
4 views
DNAS-Bench: Deterministic Nucleic Acid Screener Benchmarking

DNAS-Bench: Deterministic Nucleic Acid Screene...

Bioinformatics
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librarian
3 views
From vehicles to wildlife: transferable deep learning for trajectory generation

From vehicles to wildlife: transferable deep l...

Bioinformatics
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librarian
5 views
Interpretable Prediction of Phase Separation and Disease Variant Effects in Intrinsically Disordered Regions

Interpretable Prediction of Phase Separation a...

Bioinformatics
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librarian
4 views
multiScaleAC: Cell-Cell interaction with Moran's I as a function of kernel bandwidth

multiScaleAC: Cell-Cell interaction with Moran...

Bioinformatics
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librarian
3 views
Interpretable Peripheral Blood Cell Classification via Vision-Language Concept Bottleneck and Soft Decision Tree

Interpretable Peripheral Blood Cell Classifica...

Bioinformatics
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librarian
4 views
DPCGS: a computational framework for linking GWAS to single-cell transcriptomics in complex traits and diseases

DPCGS: a computational framework for linking G...

Bioinformatics
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Shaoxing Dai
4 views
Learnable Graph Network Model (LGNM): A Physics Constrained Graph Neural Network with Quantum Hamiltonian Learning

Learnable Graph Network Model (LGNM): A Physic...

Bioinformatics
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Bhuwan Sharma
11 views
EBD-DTI: Episodic Bridge Diffusion for Zero-Shot Cold-Start Drug-Target Interaction Prediction

EBD-DTI: Episodic Bridge Diffusion for Zero-Sh...

Bioinformatics
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librarian
5 views
GDTR: Layer-wise Settling Depth Reveals Biological Grammar in Genomic Foundation Models

GDTR: Layer-wise Settling Depth Reveals Biolog...

Bioinformatics
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librarian
4 views
Metagenomic profiling of bacterial endosymbionts in wild mutant and permethrin-susceptible head lice shows an expanded microbiota in the resistant strain

Metagenomic profiling of bacterial endosymbion...

Bioinformatics
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Jalal Mohammadi
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