Molecular Biology

A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
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David Walter
6 views
Stabilizing mammalian RNA thermometer confers neuroprotection in subarachnoid hemorrhage
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Florian Heyd
5 views
A phosphate-binding pocket in cyclin B3 is essential for XErp1/Emi2 degradation in meiosis I
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librarian
10 views
TRIM52 is a primate-specific player in the DNA repair process under tight proteolytic control by a triad of giant E3 ligases
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librarian
11 views
Development and Characterization of Recombinant ADP-Ribose Binding Reagents that Allow Simultaneous Detection of Mono and Poly ADP-Ribose
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W. Lee Kraus
11 views
Deep dive into the diversity and properties of rhodopsins in actinomycetes of the family Geodermatophilaceae
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Sergey Tarlachkov
12 views
Streptolysin O Accelerates the Conversion of Plasminogen to Plasmin
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librarian
10 views
SLAMseq reveals transfer of RNA from liver to kidney in the mouse
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Robert Hunter
12 views
Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts
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Valeria Rudman-Melnick
14 views
Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance
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Alexander Ham
8 views
Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction
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librarian
11 views
Multi-organ structural homogeneity of amyloid fibrils in ATTRv-T60A amyloidosis patients, revealed by Cryo-EM
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librarian
12 views
miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses
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Eduardo Iglesias-Gutiérrez
10 views
Combination of bortezomib and venetoclax targets the pro-survival function of LMP-1 and EBNA-3C of Epstein-Barr virus in post-transplant lymphoproliferative disorder
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Alan Chiang
8 views
BCL-2 and BOK regulate apoptosis by interaction of their C-terminal transmembrane domains
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librarian
10 views
Cyclic di-AMP regulates genome stability and drug resistance in Mycobacterium through RecA-dependent and -independent recombination
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librarian
10 views
Peroxiredoxin 2 Regulates DAF-16/FOXO Mediated Mitochondrial Remodelling in Response to Exercise that is Disrupted in Ageing
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Brian McDonagh
14 views
Full-length tRNAs lacking a functional CCA tail are selectively sorted into the lumen of extracellular vesicles
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Alan Gerber
14 views
Nuclear actin-dependent Meg3 expression suppresses metabolic genes by affecting the chromatin architecture at sites of elevated H3K27 acetylation levels
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librarian
11 views
Eluding anemone nematocysts: are clownfish deprived of N-acetylated sugars in their skin mucus?
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librarian
10 views
SNP assays for DVI: cost, time, and performance information for decision-makers
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Andreas Tillmar
12 views
A phosphorylation code coordinating transcription condensate dynamics with DNA replication
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Joshua Saldivar
11 views
Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling
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Nadine Jagerovic
9 views
Visualization of intracellular ATP dynamics in the whole kidney under pathophysiological conditions using the kidney slice culture system
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librarian
11 views
Analyzing the Involvement of Cholinesterases in the Immune Landscape of Lung Adenocarcinoma and Their Prognostic Values
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librarian
13 views
Super-enhancer interactomes from single cells link clustering and transcription
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Kevin Wang
14 views
Activation of PKR by a short-hairpin RNA
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Kyle Cottrell
14 views
N-Myc and STAT Interactor is an endometriosis suppressor.
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Sang Jun Han
18 views