Synthetic Biology

Seven mutations unlock strict synthetic methylotrophy in engineered Pseudomonas putida
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Òscar Puiggené
2 views
Continuous site-directed mutagenesis and selection in Escherichia coli
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Fabian Rehm
5 views
Pharmacologically regulated bioorthogonal stabilization domain for regulation of CAR T cells
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librarian
15 views
Overcoming protocatechuate and catechol accumulation in muconic acid production via adaptive laboratory evolution and metabolic engineering in Pseudomonas putida
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Alissa Bleem
14 views
Engineered Pseudomonas putida reconfigures metabolic fluxes to support energy demands during muconate bioproduction from lignin-related aromatics
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Allison Werner
17 views
Storing >1 byte of information in 16S ribosomal RNA using orthogonal trans-splicing ribozymes
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librarian
15 views
Pathway selection for arabinose utilization in Pseudomonas putida reveals a rate-yield tradeoff in muconic acid production from lignocellulosic sugars
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Davinia Salvachúa
11 views
Biocontainment attenuation of mobile DNA host range in a wastewater microbiome
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librarian
20 views
Minimal Data, Maximal Insight (MDMI): A Structure-guided Pipeline for Discovering Functional Alternatives in Peptide-Protein Interfaces
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Keith Pardee
10 views
Programmable and Dynamic DNA Localisation at Synthetic Cell Membranes
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librarian
16 views
A microbial growth-coupled platform for in vivo interrogation of Rubisco oxygenase activity
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Enrico Orsi
11 views
BxbI-mediated insertion of a 77kb human RET sensitive haplotype into the mouse genome to generate a humanized model of Hirschsprung disease
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librarian
15 views
Extracellular injection system combined with peptides for intracellular Staphylococcus aureus treatment
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Ningning Song
12 views
MozClo: An Expanded MoClo Toolset for Large Multigene Assembly and Plant Transformations
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Cory Tobin
13 views
Transcription-induced coacervation accelerates and sensitizes cell-free biosensing
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Samanvaya Srivastava
15 views
AAV delivered lysosome-targeting chimeras mediate sustained antibody depletion in vivo
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librarian
13 views
Fabrication and Use of a 32-Well LED-Embedded Microplate for Optogenetic Dynamic Control
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librarian
13 views
Deoxyribonucleotide incorporation reshapes mRNA design beyond canonical ribonucleotide boundaries
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Joseph Rosenecker
13 views
An Unusual Follower Peptide is Required for Biosynthesis of the Antibiotic Lasso Peptide Triculamin
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librarian
10 views
Domain Insertion Improves the Precision of a CRISPR Adenine Base Editor
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librarian
15 views
Directed evolution of compact synthetic promoters via AlphaGenome and genetic algorithms
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Linxiao Nie
17 views
Linker-Length Landscape Mapping Enables Coupling of Diverse Synthetic Chemically Induced Dimerization Systems to Molecular Readouts
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librarian
16 views
Photoswitchable optoGPCRs for reversible control of Gs and arrestin signalling
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Deborah Walter
16 views
Crowdsourced riboregulators reveal design principles for programmable RNA switching
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librarian
20 views
Synergistic CRISPR-Cas Antimicrobials through Essential and Defensive Gene Cotargeting in Staphylococcus aureus
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librarian
15 views
Targeted DNA nicking enables efficient, single-step and counterselection-free editing of bacteriophage genomes
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librarian
17 views
Complete elucidation and heterologous reconstruction of the biosynthetic pathway of camptothecin
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Zhihua Zhou
16 views