Computational screening of T-muurolol for an alternative antibacterial solution against Staphylococcus aureus infections: A state-of-the-art phytochemical-based drug discovery approach

Computational screening of T-muurolol for an a...

Pharmacology and Toxicology
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librarian
15 views
Development of a novel microphysiological system for neurotoxicity prediction using human iPSC-derived neurons with morphological deep learning

Development of a novel microphysiological syst...

Pharmacology and Toxicology
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Ikuro Suzuki
18 views
A nanobody-enzyme fusion protein targeting PD-L1 and sialic acid exerts anti-tumor effects by affecting tumor associated macrophages

A nanobody-enzyme fusion protein targeting PD-...

Pharmacology and Toxicology
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librarian
20 views
Leveraging protein language and structural modelsfor early prediction of antibodies with fast clearance

Leveraging protein language and structural mod...

Pharmacology and Toxicology
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librarian
20 views
The Niger Delta is Under a Pollution Warning: Hydrocarbon profiles in crude oil polluted soil remediated with Pleurotus ostreatus and Eisenia fitida.

The Niger Delta is Under a Pollution Warning: ...

Pharmacology and Toxicology
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librarian
56 views
Antiviral Drug Discovery with an Optimized Biochemical Dengue Protease Assay: Improved Predictive Power for Antiviral Efficacy

Antiviral Drug Discovery with an Optimized Bio...

Pharmacology and Toxicology
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librarian
18 views
Preclinical study of the human recombinant Erythropoietin (GBPD002) compared with Eprex

Preclinical study of the human recombinant Ery...

Pharmacology and Toxicology
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librarian
18 views
Arterial effects of anthracycline: structural and inflammatory assessments in non-human primates and lymphoma patients using 18F-FDG positron emission tomography

Arterial effects of anthracycline: structural ...

Pharmacology and Toxicology
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librarian
20 views
Potency, dissociation kinetics and reversibility of fentanyls and nitazenes by naloxone at the μ opioid receptor

Potency, dissociation kinetics and reversibili...

Pharmacology and Toxicology
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Graeme Henderson
23 views
Cadmium Disrupts Blood-Testis Barrier (BTB) via An Oxidative Stress-Dependent Autophagy in Prepubertal Rats

Cadmium Disrupts Blood-Testis Barrier (BTB) vi...

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librarian
22 views
Ethosuximide: subunit- and Gβγ-dependent blocker and reporter of allosteric changes in GIRK channels

Ethosuximide: subunit- and Gβγ-dependent block...

Pharmacology and Toxicology
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librarian
24 views
Protective Effects of Butyrate on Retinal Neovascularization in Preclinical Retinopathy of Prematurity Models

Protective Effects of Butyrate on Retinal Neov...

Pharmacology and Toxicology
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Ravirajsinh Jadeja
28 views
Tackling Anticancer Drug Resistance and Endosomal Escape in Aggressive Brain Tumors Using Bioelectronics

Tackling Anticancer Drug Resistance and Endoso...

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librarian
27 views
ACKR5/GPR182 is a scavenger receptor for the atypical chemokine CXCL17, GPR15L and various endogenous peptides

ACKR5/GPR182 is a scavenger receptor for the a...

Pharmacology and Toxicology
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librarian
23 views
Inhibition of Endothelial Lipase by MEDI5884 Normalizes Phosphatidylinositol Levels in Coronary Artery Disease Patients

Inhibition of Endothelial Lipase by MEDI5884 N...

Pharmacology and Toxicology
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librarian
18 views
Antinociceptive synergy in a peripheral hyperalgesia model: interplay of cannabinoidergic, adrenergic, and opioidergic systems and their antagonism

Antinociceptive synergy in a peripheral hypera...

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Caio Baeta Lopes
18 views
Direct β1/β2 AMPK activation reduces liver steatosis but not fibrosis in a mouse model of non-alcoholic steatohepatitis

Direct β1/β2 AMPK activation reduces liver ste...

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librarian
29 views
Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of oxytocin-elicited reductions of body weight and adiposity in male diet-induced obese mice

Sympathetic innervation of interscapular brown...

Pharmacology and Toxicology
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librarian
16 views
Exposure to the pesticide tefluthrin causes developmental neurotoxicity in zebrafish

Exposure to the pesticide tefluthrin causes de...

Pharmacology and Toxicology
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Fahmi Mesmar
20 views
Pharmacodynamic modeling of colistin and imipenem against in vitro Pseudomonas aeruginosa biofilms

Pharmacodynamic modeling of colistin and imipe...

Pharmacology and Toxicology
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Coen van Hasselt
19 views
Dihydromyricetin promotes GLP-1 secretion to improve insulin resistance via "gut microbiota-CDCA"

Dihydromyricetin promotes GLP-1 secretion to i...

Pharmacology and Toxicology
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Long Yi
19 views
Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diverse Caenorhabditis elegans strains

Structure-specific variation in per- and polyf...

Pharmacology and Toxicology
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librarian
18 views
Flavonoids as anxiolytics in animal tests: Bibliometry and meta-analysis of the effects of flavonoids on anxiety-like behavior in animal tests

Flavonoids as anxiolytics in animal tests: Bib...

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Caio Maximino
34 views
The 11β-hydroxysteroid dehydrogenase type 1 inhibitor SPI-62 prevents morbidity in a mouse model of Cushing's syndrome

The 11β-hydroxysteroid dehydrogenase type 1 in...

Pharmacology and Toxicology
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librarian
23 views
Protective Effect of 2-Hydroxyestrone and2-Hydroxyestradiol Against Chemically-Induced Hepatotoxicity In Vitro and In Vivo

Protective Effect of 2-Hydroxyestrone and2-Hyd...

Pharmacology and Toxicology
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librarian
26 views
Semi-Supervised Learning to Boost Cardiotoxicity Prediction by Mining a Large Unlabeled Small Molecule Dataset

Semi-Supervised Learning to Boost Cardiotoxici...

Pharmacology and Toxicology
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librarian
21 views
A Dose-Response Model for Accurate Detection and Quantification of Transcriptome-Wide Gene Knockdown for Oligonucleotide-Based Medicines

A Dose-Response Model for Accurate Detection a...

Pharmacology and Toxicology
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librarian
28 views
Reorganization of innate immune cell lipid profiles by bioinspired meroterpenoids to limit inflammation

Reorganization of innate immune cell lipid pro...

Pharmacology and Toxicology
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librarian
23 views
Microbiota-dependent in vivo biotransformation, accumulation, and excretion of arsenic from arsenobetaine-rich diet

Microbiota-dependent in vivo biotransformation...

Pharmacology and Toxicology
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librarian
20 views
An anti-SARS-CoV-2 formula consisting volatile oil from TCM through inhibiting multiple targets in cultured cells

An anti-SARS-CoV-2 formula consisting volatile...

Pharmacology and Toxicology
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librarian
16 views
Bisphenol TMC disturbs mitochondrial activity and biogenesis, reducing lifespan and healthspan in the nematode Caenorhabditis elegans

Bisphenol TMC disturbs mitochondrial activity ...

Pharmacology and Toxicology
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librarian
18 views
Sex-specific expression of the human NAFLD-NASH transcriptional signatures in the liver of medaka with a history of ancestral bisphenol A exposure

Sex-specific expression of the human NAFLD-NAS...

Pharmacology and Toxicology
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Ramji Bhandari
17 views