Kumar, A. H.; Sagar, V.; BM, R.

Background: Lumpy Skin Disease (LSD) lacks targeted treatment options and is managed using antibiotics and anti-inflammatory drugs. This study evaluated the efficacy of a polyherbal combination therapy in the management of LSD in affected bovines. Materials and Methods: 52 dairy cattle clinically diagnosed with LSD were enrolled in a field trial conducted under veterinary supervision. All animals received LUMPY NIL Herbal Powder orally at 30 g twice daily, along with topical application of LUMPY NIL Dermal Spray on closed nodules and LUMPY NIL Ointment on open wounds. Daily monitoring included clinical signs, lesion progression, systemic symptoms, and milk yield recovery. Results: Treatment duration varied from 7 to 21 days depending on severity of the disease. New lesion formation ceased within 2 to 4 days of treatment initiation. Systemic symptoms such as fever, lethargy, and inappetence resolved within 1 to 3 days. Open wounds showed progressive healing with no signs of infection, and nodules dried and sloughed off by day 15 in most animals. Milk yield showed partial recovery (20%) by day 7 and returned to baseline by day 15. The reduction in nodule size and number ranged from 81% to 94% by days 10 to 15. No adverse effects were observed during the treatment period. Conclusion: The polyherbal treatment combining demonstrated promising therapeutic benefits in managing clinical symptoms and accelerating recovery in LSD infected cattle.