Neutralisation of SARS-CoV-2 Omicron subvariants BA.2.86 and EG.5.1 by antibodies induced by earlier infection or vaccination

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Neutralisation of SARS-CoV-2 Omicron subvariants BA.2.86 and EG.5.1 by antibodies induced by earlier infection or vaccination

Authors

Lassauniere, R.; Polacek, C.; Baig, S.; Ellegaard, K.; Escobar-Herrera, L. A.; Fomsgaard, A.; Spiess, K.; Schwartz, O.; Planas, D.; Simon-Loriere, E.; Schneider, U. V.; Sieber, R. N.; Stegger, M.; Krause, T. G.; Ullum, H.; Jokelainen, P.; Rasmussen, M.

Abstract

Highly mutated SARS-CoV-2 Omicron subvariant BA.2.86 emerged in July 2023. We investigated the neutralisation of isolated virus by antibodies induced by earlier infection or vaccination. The neutralisation titres for BA.2.86 were comparable to those for XBB.1 and EG.5.1, by antibodies induced by XBB.1.5 or BA.4/5 breakthrough infection or BA.4/5 vaccination.

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