Interactive exploration of biobank-scale ancestral recombination graphs with Lorax.
Voice is AI-generated
Connected to paperThis paper is a preprint and has not been certified by peer review
Interactive exploration of biobank-scale ancestral recombination graphs with Lorax.
Katte, P.; Corbett-Detig, R.
AbstractAncestral Recombination Graphs (ARGs) underpin analyses of natural selection, disease association, and population history but remain difficult to explore at biobank scale. We introduce Lorax, a GPU-accelerated, web-native platform for real-time visualization of population-scale ARGs. Lorax integrates genomic position, coalescent time, local genealogy, and metadata, enabling interactive exploration of ancestry and variant inheritance in biobank-scale datasets.